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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease graft versus host disease
Comorbidity C0023418|leukemia
Sentences 11
PubMedID- 25778886 Objective: to explore the influence of relapse and survival by chronic graft versus host disease (cgvhd) in patients with acute myeloid leukemia (aml) after allogeneic hematopoietics stem cell transplantation (allo-hsct).
PubMedID- 24410134 Thus, we analyzed the distribution and clonality of the tcr valpha and vbeta repertoire of treg cells from leukemia patients with and without gvhd after allo-hsct.
PubMedID- 21122312 [clinical study on the relapsd leukemia patients with graft versus host disease after allogeneic hematopoietic stem cell transplantation.]
PubMedID- 26011372 Ofatumumab in a chronic lymphocytic leukemia patient with graft versus host disease and relapse after mini-allo bmt.
PubMedID- 25363669 Il-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects.
PubMedID- 21663506 Imatinib mesylate in t-cell large granular lymphocyte leukemia associated with chronic graft-versus-host disease.
PubMedID- 25778912 Mismatched hematopoietic cell transplants for treating leukemia are complicated by graft versus host disease (gvhd).
PubMedID- 22532520 In vivo, the combination reduced the risk of graft-versus-host disease without hampering graft-versus-leukemia effect, as shown in mice receiving graft-versus-host disease prophylaxis with sirolimus plus bortezomib being infused with tumor wehi cells plus c57bl/6 donor bm and splenocytes.
PubMedID- 26039207 Recent trials indicate that high doses of cd34+ progenitors from g-csf mobilized peripheral blood leukocytes isolated and t-cell depleted by immunoadsorption to paramagnetic beads, when administered after myeloablative conditioning with tbi and chemotherapy or chemotherapy alone can secure consistent engraftment and abrogate gvhd in patients with acute leukemia without incurring an increased risk of a recurrent leukemia.
PubMedID- 26445106 Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood--a report from eurocord, the acute leukemia working party, and the cord blood committee of the cellular therapy and immunobiology working party of the european group for blood and marrow transplantation.
PubMedID- 24734223 One drawback to aggressive immunomanipulation is the risk of causing gvhd in conjunction with the intended graft-vs.-leukemia (gvl) effect.

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