eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | glucosephosphate dehydrogenase deficiency |
| Comorbidity | C0024530|malaria |
| Sentences | 8 |
| PubMedID- 23175557 | In conclusion, the study of sutanto and colleagues clearly demonstrates the efficacy and safety of a single dose of 0.45 mg/kg primaquine on the third day of treatment as a gametocytocide drug in the treatment of uncomplicated falciparum malaria, excluding patients with g6pd deficiency. |
| PubMedID- 24502194 | Clinical mppt investigations revealed that malaria patients with g6pd deficiency tolerated primaquine much better than non-infected persons with the deficiency. |
| PubMedID- 25678925 | Conclusion: vivax malaria positive individuals with g6pd deficiency showed too mild symptoms of malaria or even asymptomatic. |
| PubMedID- 21203490 | This vulnerability is impressively underscored by the malaria-protective effects of glucose-6-phosphate dehydrogenase deficiency, one of the most frequent human gene defects worldwide, which leads to a lack of reducing equivalents provided by nadph [16]. |
| PubMedID- 20520804 | The frequency of phenotypic and genotypic g6pd deficiency in individuals with vivax malaria was compared against controls who had not had malaria in the previous two years. |
| PubMedID- 23384623 | The spatial extent of plasmodium vivax malaria overlaps widely with that of g6pd deficiency; unfortunately the only drug licensed for the radical cure and relapse prevention of p. |
| PubMedID- 20684792 | The fact that the prevalence of g6pd deficiency correlates with endemicity for malaria had lead to the hypotheses that g6pd deficiency may be result of natural selection conferring protection against malaria infection [2-5]. |
| PubMedID- 21849081 | Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six african countries enrolled in two randomized anti-malarial clinical trials. |
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