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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease glucosephosphate dehydrogenase deficiency
Comorbidity C0002871|anemia
Sentences 15
PubMedID- 24434750 Sexual stage p. falciparum gametocytes have a lifespan of over 3 weeks and are not cleared effectively by current antimalarial agents, except primaquine (pq)34, which is not widely used because it causes hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency5.
PubMedID- 21397531 Here we report a portuguese woman who suffered in her sixties from a chronic hemolytic anemia due to g6pd deficiency.
PubMedID- 25748035 The hemolytic anemia in g6pd deficiency is usually triggered by oxidative stress, but the mechanism remains uncertain.
PubMedID- 25756470 Metformin-induced hemolytic anemia in a patient with glucose-6-phosphate dehydrogenase deficiency.
PubMedID- 24049258 These include chills, fever, leukopenia, granulocytopenia, hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency, cholestatic jaundice.
PubMedID- 22574149 However, because malaria infection was uncommon in the present study, g6pd deficiency was not associated with anemia risk.
PubMedID- 23530079 Anti-malarial 8-aminoquinolines drugs cause acute hemolytic anemia in individuals with glucose-6-phosphate dehydrogenase deficiency (g6pdd).
PubMedID- 24913163 In a novel mouse model of hemolytic anemia associated with human g6pd deficiency, it was also demonstrated that (-)-(r)-pq was less hemolytic than (+)-(s)-pq for the g6pd-deficient human red cells engrafted in the nod-scid mice.
PubMedID- 23970095 Acute hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency complicated by ginkgo biloba.
PubMedID- 24259700 Methylene blue should not be used as an antidote because it may worsen hemolytic anemia in patients with g6pd deficiency.
PubMedID- 21502082 However, they can cause hemolytic anemia in people with glucose-6-phosphate dehydrogenase deficiency [29].
PubMedID- 21302115 Chronic nonspherocytic hemolytic anemia (cnsha) due to g6pd deficiency is rare.
PubMedID- 21612616 Among 289 participants of the 2004 study, 3 relocated their residence place, 5 could not be located, 1 child deceased due to cancer, 2 could not participate since their mothers deceased during the study period, 7 children were excluded due to birth weight of less than 2 kg or birth week less than 34. nine additional children were excluded due to thalassemia minor (3 children), type-1 diabetes (1 child), glucose-6-phosphate dehydrogenase deficiency with anemia (1 child), major heart defect (1 child), panhypopituitarism (1 child), hemophilia (1 child), and significant developmental delay requiring therapy (1 child).
PubMedID- 24052930 In fact, case reports of g6pd deficiency with severe hemolytic anemia published in japan often describe the family history of foreign mothers (shimomura et al.
PubMedID- 24223971 It has also been demonstrated that infections caused by certain viruses, such as hepatitis viruses (a, b, and e) and cytomegalovirus, were associated with hemolytic anemia in patients with g6pd deficiency [8,9].

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