eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | glucosephosphate dehydrogenase deficiency |
| Comorbidity | C0002871|anaemia |
| Sentences | 8 |
| PubMedID- 25885097 | Being aware of primaquine inducing acute haemolytic anaemia, participants with g6pd deficiency were exempted from taking part in a study that used primaquine to radically clear malaria parasites [13]. |
| PubMedID- 24502194 | Clinically significant adverse events observed following the daily 15 mg dose during the mppt consisted of symptoms and signs of moderate haemolysis and anaemia which were associated with g6pd deficiency [29]. |
| PubMedID- 24742291 | Nevertheless, primaquine may cause haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (g6pdd), a major bottleneck for its large-scale use[6,7]. |
| PubMedID- 26303162 | Background: primaquine is used to prevent plasmodium vivax relapse; however, it is not implemented in many malaria-endemic countries, including cambodia, for fear of precipitating primaquine-induced acute haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase deficiency (g6pdd). |
| PubMedID- 22607348 | Primaquine has been associated with acute haemolytic anaemia in patients with g6pd deficiency and, therefore, knowledge of the prevalence and geographical distribution of this inherited blood condition in p. vivax endemic areas is important [49]. |
| PubMedID- 20175930 | Higher doses of primaquine can cause haemolytic anaemia in individuals with g6pd deficiency, but the lower doses used in this programme are thought to be safe, based on extensive experience in malaria elimination campaigns in past decades. |
| PubMedID- 24117340 | g6pd deficiency in babies with sca worsens anaemia and increases blood transfusion requirements in the first years of life. |
| PubMedID- 25234071 | Acute haemolytic anaemia and myolysis due to g6pd deficiency. |
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