eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | glioma |
| Comorbidity | C0017636|glioblastomas |
| Sentences | 7 |
| PubMedID- 23426283 | glioblastomas (gbms) represent ∼7.5% of all intramedullary gliomas and 1 to 3% of all spinal cord tumours (4,6). |
| PubMedID- 25977481 | Mk' and mean diffusivity identified glioblastomas in the group of high-grade gliomas with similar significance and accuracy (area under the curvemk' = 0.886; area under the curvemean diffusivity = 0.876; pmk' = .003; pmean diffusivity = .004). |
| PubMedID- 25785247 | Primary glioblastomas and a subset of proneural tumors are glioma-cpg island hypermethylator phenotype (g-cimp) negative, and a large proportion are mgmt unmethylated. |
| PubMedID- 22583806 | Background: high-grade gliomas, including glioblastomas (gbms), are recalcitrant to local therapy in part because of their ability to invade the normal brain parenchyma surrounding these tumors. |
| PubMedID- 23998913 | Similar to cancer stem cells isolated from glioblastomas, stem cells of low-grade gliomas [28, 65–67] are more resistant to chemotherapeutics than their differentiated daughter cells [21]. |
| PubMedID- 22203901 | glioblastomas represent the majority of the glial tumors, but their phenotypic and genotypic heterogeneities are large, as attested by the appellation “glioblastoma multiforme”. |
| PubMedID- 23991844 | In de novo glioblastomas, the mean percentage of cd133-positive glioma cells in sections obtained at recurrence was 12.2% +/- 10.3%, which was significantly higher than that obtained at the primary surgery (1.08% +/- 1.78%). |
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