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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease glioma
Comorbidity C0004114|astrocytomas
Sentences 8
PubMedID- 21674016 astrocytomas represent 75% of all gliomas, and glioblastomas form 51.7% of cases.1 glioblastoma is the most frequent and malignant astrocytoma, and despite advances in diagnosis and treatment of these tumors, their prognosis remains dismal.4,5 the development of new effective therapies is urgently needed.
PubMedID- 23934769 The clinical characteristics of 137 samples derived from glioma patients, principally with astrocytomas, are listed in table 1. all cases had standard surgery, and the pathological material was ffpe tissue, using the same procedure at the 10th military clinical hospital of bydgoszcz.
PubMedID- 24300787 In two large independent glioma datasets, pid1 mrna was lower in glioblastomas (gbm), the most malignant gliomas, compared with other astrocytomas, oligodendrogliomas and nontumor brains.
PubMedID- 25708303 Most of these are gliomas, with astrocytomas (low grade) predominating in children and ependymomas in adults.
PubMedID- 24470548 Results: approximately 57% of pediatric cns tumors were gliomas, with astrocytomas of the pilocytic type predominating.
PubMedID- 23998913 In tumour cells, a significant increase in bmpr-ib was observed to be progressively expressed in malignant glioma compared with low-grade astrocytomas [152].
PubMedID- 25815327 For what concerns anaplastic astrocytomas, the treatment of anaplastic glioma varies depending on histopathology of the tumor, molecular markers, and individual patient characteristics.
PubMedID- 22433833 In this review we describe the pathobiology, molecular pathogenesis, stem cells and imaging characteristics of gliomas with emphasis on astrocytomas and oligodendroglial neoplasms.

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