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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease glioblastoma
Comorbidity C0004114|astrocytomas
Sentences 8
PubMedID- 22773464 The nuclear translocation of both molecules was observed in astrocytomas with glioblastoma transition, or glioblastoma tissues.
PubMedID- 21206896 astrocytomas, including glioblastoma multiforme (gbm), are the most common malignant central nervous system (cns) tumors in neurosurgical practice.
PubMedID- 24039448 There was no statistically significant difference regarding perivascular cd3 infiltrate in glioblastomas compared with pilocytic astrocytomas (p = 0.235).
PubMedID- 21674016 astrocytomas represent 75% of all gliomas, and glioblastomas form 51.7% of cases.1 glioblastoma is the most frequent and malignant astrocytoma, and despite advances in diagnosis and treatment of these tumors, their prognosis remains dismal.4,5 the development of new effective therapies is urgently needed.
PubMedID- 20423517 High-resolution copy number analysis of glioma samples also revealed recurrent gain of multiple sub-regions of chromosome 12 in secondary glioblastomas arising from lower grade astrocytomas [45].
PubMedID- 20704656 In this study 59 paediatric pilocytic astrocytomas were compared with 62 adult glioblastomas, as a prototype of tumour angiogenesis.
PubMedID- 24610491 In brain tumors, glur1 subunit was differentially expressed according to the tumor grading, being elevated in glioblastomas when compared with anaplastic astrocytomas and low-grade astrocytomas, hence correlating with tumor aggressiveness (de groot et al.
PubMedID- 23258846 Results: mct1, mct4, and cd147 were overexpressed in the plasma membrane of glioblastomas, compared with diffuse astrocytomas and nonneoplastic brain.

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