eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | glioblastoma |
| Comorbidity | C0004114|astrocytoma |
| Sentences | 6 |
| PubMedID- 21674016 | astrocytomas represent 75% of all gliomas, and glioblastomas form 51.7% of cases.1 glioblastoma is the most frequent and malignant astrocytoma, and despite advances in diagnosis and treatment of these tumors, their prognosis remains dismal.4,5 the development of new effective therapies is urgently needed. |
| PubMedID- 20860896 | glioblastoma with granular cell astrocytoma features: a case report and literature review. |
| PubMedID- 21663411 | Perivascularly, cd68-positive infiltrate was also more prevalent in glioblastoma when compared with pilocytic astrocytoma (97% vs 86%, respectively; p = 0.0003). |
| PubMedID- 21193945 | In contrast to pilocytic astrocytoma, evaluation of the pediatric glioblastoma expression dataset [11] showed minimal expression of omg (mean expression measure = 416.2(81.3)).1 however, olig2, olig1, and gfap were highly expressed in pediatric glioblastoma (mean expression measures 1085.9 (117.1), 2609.4 (426.5), 5499.8 (731), respectively) (see footnote 1).table 7differential expression of neural lineage genesgene namegenbank #diff exp in olig2 null (y/n) mean expm-ep (st. |
| PubMedID- 21804458 | Only secondary glioblastomas (arising from low grade astrocytoma) were positive for c-erbb-2 protein, and all of the primary (arising “de novo”) glioblastoma were negative for c-erbb-2 protein. |
| PubMedID- 26165699 | We found that rab27b was hypomethylated in high-grade glioma (anaplastic gliomas and glioblastomas) compared with low-grade glioma (astrocytoma, oligodendrocytoma and oligoastrocytoma) (p=0.02). |
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