eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | focal segmental glomerulosclerosis |
| Comorbidity | C0022658|nephropathy |
| Sentences | 13 |
| PubMedID- 25968128 | In mice with adriamycin nephropathy, a model of human fsgs, blocking the synthesis of retinoic acid resulted in elevated proteinuria and exacerbated glomerulosclerosis, while treatment with retinoic acid reduced proteinuria and increased podocyte number [22]. |
| PubMedID- 21698141 | Interaction analyses between frmd3 snps were repeated in non-diabetic nephropathy cases (with biopsy-proven fsgs and hivan) and interactions were not observed. |
| PubMedID- 23949798 | In mice with adriamycin nephropathy, a model of human fsgs, blocking endogenous retinoic acid synthesis increased proteinuria and exacerbated glomerulosclerosis. |
| PubMedID- 24308295 | He commented that iga nephropathy patients with fsgs-like lesions have a similarly poor prognosis as idiopathic fsgs patients. |
| PubMedID- 20051853 | Genetic analyses in patients with essential hypertension and nephropathy attributed to hypertension, focal segmental glomerulosclerosis and hivan reveal that myh9 gene polymorphisms are associated with a spectrum of kidney diseases in this ethnic group. |
| PubMedID- 26089920 | Although an and remnant kidney models both resemble human fsgs, adriamycin nephropathy, which induces podocyte oxidative stress, fostered the concept of primary podocyte injury in the pathogenesis of foot process effacement and glomerulosclerosis. |
| PubMedID- 22844593 | Podocytopathies (minimal change disease (mcd) and focal segmental glomerulosclerosis (fsgs)) together with membranous nephropathy are the main causes of nephrotic syndrome. |
| PubMedID- 21279725 | Here we report the use of rituximab in four children with idiopathic steroid-resistant nephrotic syndrome (srns) with various histological backgrounds (two cases with focal segmental glomerulosclerosis, one case with igm nephropathy, and one case with minimal change disease), who failed to respond to other immunsuppressions. |
| PubMedID- 24460887 | Proteinuria and fsgs in rats with puromycin nephropathy were shown to worsen with cholesterol intake [18], and joles et al. |
| PubMedID- 25107948 | Their levels were compared both under different treatment responses in a prospective study of fsgs and in patients with different membranous nephropathy (mn) and diabetic nephropathy (dn) disease activity. |
| PubMedID- 23552865 | Osteopontin (opn) expression has been reported to be elevated in experimental models of renal injury such as arterial hypertension or diabetic nephropathy finally leading to focal segmental glomerulosclerosis (fsgs). |
| PubMedID- 22282598 | In addition to the classic hiv-1-associated nephropathy with collapsing-type focal segmental glomerulosclerosis and characteristic tubulocystic changes, which is more common in afro-american than in caucasian hiv-1 patients, immune complex gns such as membranous gn and membranoproliferative gn are particularly common renal manifestations. |
| PubMedID- 20090504 | Mitochondrial nephropathy with fsgs is diagnosed by genetic analysis or electron microscopy when it is suspected. |
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