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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease fetal alcohol syndrome
Comorbidity C0679466|cognitive deficits
Sentences 2
PubMedID- 20488644 These data suggest that repeated in vivo exposure to elevated ethanol doses during the third trimester-equivalent period impairs synaptic plasticity, which may alter maturation of hippocampal circuits and ultimately contribute to the long-lasting cognitive deficits associated with fetal alcohol spectrum disorders.
PubMedID- 23647404 Background: effective treatments for the behavioral and cognitive deficits in children with fetal alcohol spectrum disorders (fasd) are lacking, and translational approaches using animal models can help develop rational interventions.

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