eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | familial breast cancer |
| Comorbidity | C0006142|breast cancer |
| Sentences | 3 |
| PubMedID- 19763692 | Background: the lifetime risk of breast cancer (bc) in patients with hereditary breast cancer syndromes is as high as 80%. |
| PubMedID- 22434525 | In spite the close association of the triple-negative breast cancer immunophenotype with hereditary breast cancers and the brca1 pathway, there is a lack of population studies that determine the frequency of brca1 mutations among triple-negative breast cancer patients. |
| PubMedID- 24188377 | These findings suggest that aldh cell positivity in microscopically normal breast tissue should be further evaluated as a potential marker for the risk of breast cancer, especially in patients with familial breast cancer with or without brca1/2 mutations. |
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