eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | enhanced s-cone syndrome |
| Comorbidity | C0023418|leukemia |
| Sentences | 3 |
| PubMedID- 25960670 | It modulates the functions of different cellular responses, including cell proliferation, growth, adhesion, and death, in addition to inducing tumorigenesis.84 activation of akt1 signaling is sufficient to maintain the pluripotency of murine escs without leukemia inhibitory factor (figure 3).85 however, despite what might be expected, treatment of murine escs with the pi3k inhibitor ly294002 promoted a loss of esc characteristics, even in the presence of leukemia inhibitory factor.86 further, initiation of pi3k signaling is critical to the advancement of dedifferentiation in embryonic germ cells from primordial germ cells.87 the role of the pi3k pathway in esc biology and in reprogramming remains largely unknown. |
| PubMedID- 21608077 | Wild-type (wt) and mutant escs were maintained with leukemia inhibitory factor (lif) (chemicon, temecula, pa, http://www.chemicon.com) on gelatinized tissue culture dishes in esc media [13]. |
| PubMedID- 24114723 | Study design/materials and methods: mouse embryonic stem cells (escs) maintained with and without leukemia inhibitory factor (lif), embryoid bodies (ebs), and eb-derived cells undergoing spontaneous differentiation toward the hematopoietic lineage have been used as a sample models. |
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