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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease encephalopathy
Comorbidity C0023890|cirrhosis
Sentences 47
PubMedID- 21160996 A 66-year-old female with cryptogenic cirrhosis complicated by ascites, hepatic encephalopathy, variceal bleeding and malnutrition with meld of 34 underwent orthotopic deceased donor liver transplantation performed with piggyback technique.
PubMedID- 24709242 Objective: to determine the efficacy of rifaximin in prevention of repeated episodes of hepatic encephalopathy in patients with liver cirrhosis as compared to placebo.
PubMedID- 25867912 Objective: to determine the efficacy of rifaximin once a day dose in the prevention of hepatic encephalopathy (he) in patients with liver cirrhosis as compared with twice daily dose of rifaximin.
PubMedID- 25500314 Identification of minimal hepatic encephalopathy in patients with cirrhosis based on white matter imaging and bayesian data mining.
PubMedID- 25420513 Long term results of balloon-occluded retrograde transvenous obliteration for portosystemic shunt encephalopathy in patients with liver cirrhosis and portal hypertension.
PubMedID- 21306407 Results: it was generally agreed that severity assessment of hepatic encephalopathy in patients with cirrhosis, whether made clinically or more objectively, should be continuous rather than categorical, and a system for assessing the sonic (spectrum of neuro-cognitive impairment in cirrhosis) was proposed.
PubMedID- 25847088 Aim: to examine whether the brain exhibits metabolic disorder prior to overt hepatic encephalopathy in patients with liver cirrhosis (lc), the intracerebral glutamine and myo-inositol levels were determined using 3.0-tesla (t)1 h (proton) magnetic resonance spectroscopy (mrs).
PubMedID- 25374704 He had cirrhosis which was complicated by hepatic encephalopathy and portal hypertension including bleeding esophageal varices and ascites.
PubMedID- 23111819 The presence of portal hypertension and cirrhosis with encephalopathy could be poor prognostic factors for patients undergoing hae, especially if they are further complicated by pulmonary hypertension and cardiac failure.
PubMedID- 25846450 The development of overt hepatic encephalopathy (he) in a patient with cirrhosis confers a damning prognosis with a 1-year mortality approaching 64%.
PubMedID- 23158131 The aims of this study were to reveal the significance of cohb in patients with hepatitis b virus-related cirrhosis (hbc) complicated by hepatic encephalopathy (he), and to further investigate the influence of the ho/co pathway on the end-stage cirrhosis, hoping to find a reliable indicator to evaluate the course of hbc.
PubMedID- 21480337 Recent studies using anti-inflammatory agents such as ibuprofen and indomethacin have shown promise for the treatment of mild encephalopathy in patients with cirrhosis, whereas treatment with minocycline, a potent inhibitor of microglial activation, attenuates the encephalopathy grade and prevents brain edema in experimental acute liver failure.
PubMedID- 20508990 Diagnosis and prognostic significance of minimal hepatic encephalopathy in patients with cirrhosis of liver.
PubMedID- 20602681 Risk factors for hepatic encephalopathy in patients with cirrhosis and refractory ascites: relevance of serum sodium concentration.
PubMedID- 25755452 Inhibitory control test for the detection of minimal hepatic encephalopathy in patients with cirrhosis of liver.
PubMedID- 25528831 The data on the positive experience with hepatic encephalopathy in patients with cirrhosis liver l-ornithine-l-aspartate (drug larnamyn), the effectiveness of which is provided by its components (amino acids, ornithine and aspartate) which improve metabolism, ammonia detoxification mechanism, production of energy in the krebs cycle, promote restoration of the cell membrane, and carried out anti-inflammatory and detoxicative effect.
PubMedID- 23225825 Previously studies have investigated the effect of propofol on sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis.11,18 these studies found that propofol sedation during upper gastrointestinal endoscopy did not cause acute deterioration of sub-clinical hepatic encephalopathy.11,18 however, in patients with liver cirrhosis, hepatic function reserve is quite limited, and a cirrhotic liver is less tolerant to hemodynamic changes and surgical stress.1 therefore, anesthetic agents should be titrated with caution in cirrhotic patients to minimize the adverse effects of drugs and to stabilize hemodymanics.
PubMedID- 26417275 In a prospective, randomized controlled trial conducted by lunia et al., probiotics were found to be effective in preventing hepatic encephalopathy in patients with cirrhosis (lunia et al., 2013[104]).
PubMedID- 25212730 Embolization of spontaneous splenorenal shunt for after-tips hepatic encephalopathy in a patient with cirrhosis and variceal bleeding.
PubMedID- 21372353 Profile of hepatic encephalopathy in children with cirrhosis and response to lactulose.
PubMedID- 23731902 Background: the aim of the present study was to examine the association of diabetes mellitus (dm) with the prevalence and severity of hepatic encephalopathy (he) in patients with decompensated cirrhosis (dc) and determine the impact of age and gender on this relationship.
PubMedID- 20482828 Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin ii receptor blocker combination therapy: a case report.
PubMedID- 20939401 Hepatic encephalopathy in patients with cirrhosis may present under various clinical aspects, although minimal and episodic forms are the most frequent in clinical practice.
PubMedID- 25068951 Among the 130 patients who survived ≥90 days after admission, 66 (51%) were complicated by liver cirrhosis, including 22 with encephalopathy, and 21 with ascites.
PubMedID- 25674427 Supplementation with bcaas normalizes amino acid profiles, ameliorates complications such as encephalopathy and hypoalbuminemia in patients with liver cirrhosis (kawaguchi et al.
PubMedID- 23463488 Satavaptan did not reduce the frequency of hepatic encephalopathy in patients with cirrhosis and ascites.
PubMedID- 21922877 The aim of this study was to asses the efficacy of probiotics in minimal hepatic encephalopathy in patients with cirrhosis of the liver.
PubMedID- 25316890 This case highlights the importance of keeping direct portopulmonary venous anastomosis in the differential diagnosis of oxygen-refractory hypoxemia and recurrent hepatic encephalopathy in patients with cirrhosis in the appropriate clinical context.
PubMedID- 23485720 Lactulose is highly potential in prophylaxis of hepatic encephalopathy in patients with cirrhosis and upper gastrointestinal bleeding: results of a controlled randomized trial.
PubMedID- 20943084 Results: serum cps-i and oct levels in cirrhosis patients with hepatic encephalopathy were (143.3+/-48.5) u/l, (297.0+/-102.6) is multiplied by 10 u/l, which were lower than that in cirrhosis patients without hepatic encephalopathy (180.3+/-51.5) u/l, (351.8+/-109.0) is multiplied by 10 u/l (t = 2.53, t = 2.78, p < 0.01).
PubMedID- 23986848 A large spontaneous portal-systemic shunt is the most frequent cause of recurrent or persistent hepatic encephalopathy in patients with cirrhosis and no history of surgical or transhepatic portosystemic shunts; this was true in 71% of patients in a recent case-control study (13).
PubMedID- 23006459 Minimal hepatic encephalopathy in patients with cirrhosis by measuring liver stiffness and hepatic venous pressure gradient.
PubMedID- 22195250 Patients were considered to have acute liver failure (alf) according to the widely accepted definition of alf, which includes evidence of coagulation abnormality, usually an international normalized ratio (inr) ≥1.5, and any degree of mental alteration (encephalopathy) in a patient without pre-existing cirrhosis and with an illness of <26 weeks duration, with the exception of liver cirrhosis caused by vertically-acquired hbv if the disease has been recognized for <26 weeks.5 the definition for acute renal failure (arf) was an increase in serum creatinine concentration ≥0.5 mg/dl or by 50% compared with baseline value.6 gastrointestinal bleeding was defined as when patients presented with hematemesis, melena or hematochezia and had a drop in hemoglobin ≥1.5 g/dl.
PubMedID- 20852922 The mean cff was higher in patients after liver transplantation, but did not reach statistical significance.table 2surrogate markers for hepatic encephalopathy in patients with liver cirrhosis and those who have received liver transplants.
PubMedID- 22727021 The most widely accepted definition of alf includes evidence of coagulation abnormality, usually an inr ≥ 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks duration [1].
PubMedID- 21234351 Several controlled clinical studies reported no efficacy of bcaas on encephalopathy grade in patients with cirrhosis [95, 96].
PubMedID- 20301444 Portal hypertension and cirrhosis can lead to hepatic encephalopathy and life-threatening esophageal varices.
PubMedID- 26206073 Diabetes as a risk factor for hepatic encephalopathy in cirrhosis patients.
PubMedID- 22666568 In cirrhosis the onset of hepatic encephalopathy is related to precipitating factors that expose the brain to toxins.
PubMedID- 24459638 The most widely accepted definition of alf includes evidence of coagulation abnormality, usually an international normalized ratio (inr) ≥1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks' duration.4 alf manifests itself in a much different fashion than does aclf.
PubMedID- 22870180 Here we report on a patient suffered from liver cirrhosis with recurrent hepatic encephalopathy who developed mnz-induced neurotoxicity.
PubMedID- 21897555 We describe a case of an hbv-associated decompensated cirrhosis of liver with hepatic encephalopathy who developed cryptococcal pleural effusion and cryptococcal yeasts were demonstrated microscopically in stained smears of pleural fluid.
PubMedID- 21187868 Ascites is the most common of the three major complications of cirrhosis together with hepatic encephalopathy and variceal hemorrhage.
PubMedID- 24665321 Blood ammonia levels are often measured in patients with cirrhosis suspected of having hepatic encephalopathy, but this is not a trustworthy indicator, because many conditions and even prolonged application of tourniquet during blooddrawing can elevate blood ammonia levels (table 4).
PubMedID- 19903725 Standardized nomenclature has been proposed but a standardized approach to the treatment, particularly of persistent, episodic and recurrent encephalopathy associated with liver cirrhosis has not been proposed.
PubMedID- 21406085 The criteria for alf[17]: (aasld position paper: the management of acute liver failure, 2005) include evidence of coagulation abnormality, usually an inr ≥ 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of < 26 weeks duration.
PubMedID- 24628464 Background: safety of individual probiotic strains approved under investigational new drug (ind) policies in cirrhosis with minimal hepatic encephalopathy (mhe) is not clear.

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