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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease down syndrome
Comorbidity C0023470|myeloid leukemia
Sentences 10
PubMedID- 25231553 Prognosis and management of acute myeloid leukemia in patients with down syndrome.
PubMedID- 25887863 Transient abnormal myelopoiesis (tam) and myeloid leukemia associated with down syndrome (ml of ds) have morphologically indistinguishable blasts.
PubMedID- 22392565 Favorable survival maintained in children who have myeloid leukemia associated with down syndrome using reduced-dose chemotherapy on children's oncology group trial a2971: a report from the children's oncology group.
PubMedID- 24962331 Background: most down syndrome children with acute myeloid leukemia (ds-aml) have an overall excellent prognosis, however, patients who suffer an induction failure or relapse, have an extremely poor prognosis.
PubMedID- 22776818 myeloid leukemia in down syndrome (ml-ds) is associated with good response to chemotherapy and favorable prognosis.
PubMedID- 21557456 Background: the aim of the jcclsg aml 9805 down study was to evaluate the effect of continuous and high-dose cytarabine combined chemotherapy on the survival outcome of acute myeloid leukemia (aml) with down syndrome (ds).
PubMedID- 25587735 Approximately 20%-30% of tam survivors are at risk of development of acute myeloid leukemia (myeloid leukemia associated with down syndrome, ml-ds).
PubMedID- 26481183 Background: on the basis of results of previous japanese trials for myeloid leukemia in down syndrome (ml-ds), the efficacy of risk-oriented therapy was evaluated in the japanese pediatric leukemia/lymphoma study group aml-d05 study.
PubMedID- 20113894 myeloid leukemia in children with down syndrome is preceded by a preleukemic clone (transient leukemia or transient myeloproliferative disorder), which may disappear spontaneously, but may also need treatment in case of severe symptoms.
PubMedID- 22150305 myeloid leukemia in down syndrome.

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