eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | down syndrome |
| Comorbidity | C0023462|acute megakaryoblastic leukemia |
| Sentences | 7 |
| PubMedID- 25361478 | acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype. |
| PubMedID- 25302938 | acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype. |
| PubMedID- 25266042 | acute megakaryoblastic leukemia with acquired trisomy 21 and gata1 mutations in phenotypically normal children. |
| PubMedID- 25932450 | A case of pentasomy 21 with two isochromosome 21s in acute megakaryoblastic leukemia associated with down syndrome. |
| PubMedID- 23467713 | One case of acute megakaryoblastic leukemia (amkl) with trisomy 21, trisomy 14 and unmutated gata1 gene in a phenotypically normal girl was reported. |
| PubMedID- 22937757 | In particular, the somatic mutation of the gata1 gene, which leads to the production of n-terminally truncated gata1, contributes to the genesis of transient myeloproliferative disorder and acute megakaryoblastic leukemia in infants with down syndrome. |
| PubMedID- 23980066 | Development of acute megakaryoblastic leukemia in down syndrome is associated with sequential epigenetic changes. |
Page: 1