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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease dengue fever
Comorbidity C0019158|hepatitis
Sentences 5
PubMedID- 24628767 The histopathological findings of fulminant hepatitis associated with dengue haemorrhagic fever is often characterized by hepatocellular necrosis, typically localizing to zone 1 and 2 of the hepatic plate, a cellular inflammatory infiltrate and fatty changes.
PubMedID- 22666132 hepatitis associated with dengue fever is also characterized by moderate hepatocytes necrosis, microvesicular steatosis and cellular infiltration [31–33].
PubMedID- 20459677 Severe hepatitis in dengue infection has got worse outcome in terms of length of stay, mortality and complications as compared to mild to moderate hepatitis.
PubMedID- 24701072 [3] although, severe hepatitis associated with dengue fever is a rare occurrence, it carries significant mortality and morbidity.
PubMedID- 20362495 Conclusion: plasma leakage, severe thrombocytopenia and acute hepatitis identified subgroups of adult dengue patients with increased mortality rates.

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