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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cushing syndrome
Comorbidity C0020456|hyperglycemia
Sentences 3
PubMedID- 23558873 Background: mifepristone is approved to control hyperglycemia in adults with endogenous cushing's syndrome and is described as a mildly qtc prolonging drug, based on a tqt study.
PubMedID- 25560275 Mifepristone, a glucocorticoid receptor antagonist, has been approved for hyperglycemia associated with cushing's syndrome based on the results of a prospective study where it produced in the majority of patients' significant clinical and metabolic improvement.
PubMedID- 22674211 Mifepristone (a glucocorticoid receptor antagonist) is another promising drug, recently approved by the fda for treatment of hyperglycemia associated with cushing's syndrome.

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