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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cushing disease
Comorbidity C0001430|adenoma
Sentences 9
PubMedID- 23553862 Context: it is often difficult to find an adenoma in patients with cushing's disease (cd) whose preoperative magnetic resonance imaging (mri) is normal.
PubMedID- 24683487 The ability of mri to detect pituitary acth-secreting adenoma in patients with cushing's disease is limited because the calculated accuracy for detecting a pituitary source of acth is reportedly around 60% with conventional mri.
PubMedID- 24348593 Nelson's syndrome nowadays a rare entity results from an adrenocorticotropin (acth)-secreting pituitary adenoma in patients with refractory cushing's disease after a therapeutic bilateral adrenal gland removal.
PubMedID- 22918543 This paper reviews the available literature for medical-therapy-induced adenoma volume reduction in patients with cushing's disease and reports the experience of a 53-year-old surgically, radiologically and medically naive (de novo) female with a pituitary macroadenoma who declined surgery.
PubMedID- 23957196 While cushing disease, resulting from an acth-secreting adenoma, commonly manifests as weight gain with growth deceleration in children, gh excess causes gigantism with rapid, accelerated growth inappropriate for the height of the family.
PubMedID- 21603170 The development of autoimmune thyroid diseases has been reported after unilateral adrenalectomy for cushing's syndrome [10], after bilateral adrenalectomy in a patient with carney's complex [11] and after removal of acth-producing pituitary adenoma in patients with cushing's disease [11].
PubMedID- 25639317 In 3 of these patients, a transformation from silent to functioning acth adenoma with manifest cushing disease occurred.
PubMedID- 23605695 Pasireotide (signifor((r))) is a new subcutaneous somatostatin analogue that acts via somatostatin receptors to inhibit the secretion of corticotropin from the pituitary adenoma in patients with cushing's disease.
PubMedID- 25885309 [2] of the various causes of cushing's syndrome, cushing's disease resulting from pituitary adenoma is still rare.

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