eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cryoglobulinemia |
| Comorbidity | C0042384|vasculitis |
| Sentences | 12 |
| PubMedID- 21053035 | cryoglobulinaemia associated with systemic vasculitis mediated by immune complexes is a rare combination. |
| PubMedID- 22956970 | All 18 patients had type ii mixed cryoglobulinemia, with symptoms of vasculitis in 13. clinical symptoms of cryoglobulinemia preceded the diagnosis of lymphoma in 7 patients (at a mean time of 3.5 years before lymphoma diagnosis) and were concurrent in the other 6 patients. |
| PubMedID- 22937435 | Although leukocytoclastic vasculitis is more characteristic of mixed cryoglobulinemia, it can be a presenting manifestation of type 1 cryoglobulinemia. |
| PubMedID- 23328357 | The cryofibrinogen assay was positive without cryoglobulinaemia and other causes of vasculitis were ruled out. |
| PubMedID- 21049729 | In this report, the clinical course of a patient with established psoriasis who received rituximab therapy for vasculitis associated with mixed cryoglobulinemia (mc) type ii is described. |
| PubMedID- 22087127 | However, ifn-α may induce vasculitis with or without cryoglobulinemia, and can increase preexisting ischemia, leading to purpura, skin ulcerations, arthritis or ischemic polyneuropathy [24][25]. |
| PubMedID- 21188196 | An appropriate approach to treatment of severe acute flares of cryoglobulinemia with glomerulonephritis or vasculitis is combination antiviral therapy using peginterferon and ribavirin for 48 weeks, adding corticosteroids and cyclophosphamide as needed to control severe symptoms. |
| PubMedID- 24424176 | Cryoglobulinemic vasculitis in the presence of mixed-type cryoglobulinemia, preliminary classification criteria have been defined. |
| PubMedID- 20952479 | Objective: to describe hepatitis c virus (hcv)-related systemic vasculitis in patients without detectable mixed cryoglobulinemia (mc) and to compare them to typical cases of hcv-mc vasculitis. |
| PubMedID- 20506150 | Objective: an uncommon manifestation of hepatitis c virus (hcv) infection is systemic vasculitis associated with type ii cryoglobulinemia (cryoglobulinemic vasculitis), a proliferative b cell disorder that transforms into b cell malignancy in 5-10% of patients. |
| PubMedID- 25659437 | In another report, reactivation of cerebral toxoplasmosis after rtx therapy in a 71-year-old female with cutaneous vasculitis associated with type i cryoglobulinemia was described [14]. |
| PubMedID- 23237994 | Rituximab is also an option in essential mixed cryoglobulinemia with uncontrolled vasculitis despite glucocorticoid and/or immunosuppressive treatment. |
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