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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cryoglobulinemia
Comorbidity C0017658|glomerulonephritis
Sentences 9
PubMedID- 23293553 The most common renal manifestations of hcv infection are essential mixed cryoglobulinemia leading to membranoproliferative glomerulonephritis (mpgn), mpgn without cryoglobulinemia, and membranous glomerulonephritis.
PubMedID- 23197954 Here, we report on an exceptional case of mixed essential cryoglobulinemia with severe glomerulonephritis characterized by a prominent infiltration of the glomeruli by neutrophils.
PubMedID- 23689581 Type i membranoproliferative glomerulonephritis associated with type ii cryoglobulinemia is the most frequent association.
PubMedID- 22690241 The possible role of hcv/ns3 protein in the pathogenesis of hcv-associated mc is also suggested by another study evidencing ns3 deposits in the kidney of viremic hcv-positive patients with membranoproliferative glomerulonephritis associated with cryoglobulinemia and presenting a mild polyclonal b lymphocytosis [71].
PubMedID- 25949468 Most of these patients have immunological phenomena related to virus antigenicity, resulting in immune complex disease, usually membranoproliferative glomerulonephritis with or without cryoglobulinaemia [2].
PubMedID- 21188196 An appropriate approach to treatment of severe acute flares of cryoglobulinemia with glomerulonephritis or vasculitis is combination antiviral therapy using peginterferon and ribavirin for 48 weeks, adding corticosteroids and cyclophosphamide as needed to control severe symptoms.
PubMedID- 21426893 Membranoproliferative glomerulonephritis associated with type ii cryoglobulinemia is the predominant type of hcv-related glomerulonephritis.
PubMedID- 25815169 A single case report of its successful use in type 2 cryoglobulinaemia with membranoproliferative glomerulonephritis (mpgn) has been published (peak creatinine 248 µmol/l, final creatinine 133 µmol/l) [62], but no trials are registered for its use in rpgn.
PubMedID- 21603155 Membranoproliferative glomerulonephritis (mpgn), with or without cryoglobulinemia is the most common renal lesion associated with chronic hcv infection in the renal transplant recipients [74, 75].

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