eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | crest syndrome |
| Comorbidity | C0008925|cleft palate |
| Sentences | 4 |
| PubMedID- 23861062 | In zebrafish, untreated pdgfra mutants have cleft palate due to defective neural crest cell migration, whereas pdgfra heterozygotes develop normally. |
| PubMedID- 23483067 | Methods and material: in this study we evaluated 10 patients who underwent secondary alveolar bone grafting for various types of cleft palate with autologous iliac crest graft. |
| PubMedID- 23776616 | Augmented bmpria-mediated bmp signaling in cranial neural crest lineage leads to cleft palate formation and delayed tooth differentiation. |
| PubMedID- 23028347 | Studies in mice have demonstrated that failure to down regulate pax3 during neural crest differentiation leads to cleft palate, due to inhibitory effects on osteogenesis [40]. |
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