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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease costello syndrome
Comorbidity C0175704|leopard syndrome
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PubMedID- 24156711 However, there are unique signs by which the syndromes can differ from each other, especially multiple lentigo in leopard syndrome, increased risk of malignancy in costello syndrome, dry hyperkeratotic skin in patients with cardio-facio-cutaneous syndrome, and neurofibromas and cafe-au-lait spots in neurofibromatosis-noonan syndrome.

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