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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease complex regional pain syndrome
Comorbidity C0013421|dystonia
Sentences 12
PubMedID- 23555946 The study shows reduced force feedback weights in crps-patients with fixed dystonia, making it the first to demonstrate disturbed integration of force feedback in fixed dystonia, an important step towards understanding the pathophysiology of fixed dystonia.
PubMedID- 21609429 The aberrant reflex pattern that most closely mimicked the fixed dystonia in patients with crps was imbalanced reflex sensitivity to muscle force feedback.
PubMedID- 25254100 Conventional therapies for the treatment of crps-1 with dystonia have poor efficacy.
PubMedID- 23541068 crps patients with dystonia had an increased 2-point discrimination as compared to controls and crps patients without dystonia.
PubMedID- 21190049 Though disturbances in temperature sensation were earlier shown in crps patients without dystonia, its presence in those with dystonia is unknown.
PubMedID- 20373359 dystonia in complex regional pain syndrome type i.
PubMedID- 24120462 Our findings point at a catabolic state in chronic crps patients with dystonia that is likely associated with inflammation.
PubMedID- 21903461 Significance: this study suggests that crps-patients with dystonia are not hyperreflexive.
PubMedID- 20356382 No controlled studies have been carried out on the treatment of either dystonia or spasms in patients with crps-i.
PubMedID- 22923151 Recently, a group of movement disorder specialists, who have studied fixed dystonia in crps patients, have stated:“traditional medical dualism polarizes opinion as to whether fixed dystonia is best characterized as a psychogenic or an organic disorder.
PubMedID- 23941915 Except for a lower vibration threshold in the contralateral leg of crps patients with dystonia, no differences in sensory modalities were found between crps patients with and without dystonia.
PubMedID- 20066431 Because different mutations in the same gene can result in diverse phenotypes, we sequenced all coding exons of the dyt1, dyt5a, dyt5b, dyt6, dyt11, dyt12, and dyt16 genes in 44 crps patients with fixed dystonia to investigate whether high-penetrant causal mutations play a role in crps.

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