eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | chronic pain |
| Comorbidity | C0011570|depression |
| Sentences | 47 |
| PubMedID- 20694178 | Whitley-reed10 reports that grief therapy is effective in reducing pain and depression in a group of chronic pain sufferers. |
| PubMedID- 24195207 | Objective: to compare the difference in the clinical efficacy on depression with chronic pain between the simple medication of selective serotonin uptake inhibition antidepressants (ssris) and the combined therapy of acupuncture and ssris. |
| PubMedID- 20838499 | There is a bidirectional complex relationship between pain and depression with chronic pain as a predictor of subsequent major depression, and vice versa. |
| PubMedID- 23426854 | Applying cumulative inequality theory, this study examines the extent to which childhood socioeconomic disadvantage and maternal depression increase the risk of major depression and chronic pain in u.s. |
| PubMedID- 25983704 | Over the past 30 years, health psychologists have discovered that not just the intensity of pain, but the fear of pain is associated with functional disability, physical inactivity, and feelings of anxiety and depression in patients with chronic pain disorder (mccracken et al., 1992; vlaeyen et al., 1995; asmundson et al., 1999; crombez et al., 1999; zale et al., 2013). |
| PubMedID- 26445480 | Interaction between depression and ethnicity with both chronic pain outcomes was assessed and was indicated for some sub-groups at approximately p = 0.10. for both chronic pain outcomes (presence and extent of chronic pain), levels of adjustment for the regression models were as follows: 1) univariate analysis (no adjustment); 2) adjusted for sociodemographic variables – age, sex and quintiles of townsend score; 3) adjusted for sociodemographic and lifestyle variables – as in 2) plus smoking status, frequency of alcohol consumption and bmi; 4) adjusted for sociodemographic, lifestyle and morbidity count – as in 3) – plus number of long-term conditions reported. |
| PubMedID- 25902153 | Although separate lines of research have demonstrated positive associations between pain catastrophizing and pain-related anxiety, and both neuroticism and depression among persons with chronic pain, we are not aware of any studies that tested the relative contribution of these factors in the same statistical model. |
| PubMedID- 25370278 | The diagnosis of major depression in patients with chronic pain requires differentiation between the symptoms of pain and symptoms of physical illness. |
| PubMedID- 23738197 | Although sleep alterations are considered an important risk factor for psychological dysfunction and mental illness, these symptoms are seldom assessed together with depression and anxiety in patients with injury-related chronic pain. |
| PubMedID- 24399578 | Complementary or psychological therapies may be beneficial for those patients who have failed other options or have depression associated with chronic pain. |
| PubMedID- 24532393 | Background: chronic pain with comorbid depression is characterized by poor mood regulation and stress-related pain. |
| PubMedID- 24518228 | 4-methylcatechol prevents derangements of brain-derived neurotrophic factor and trkb-related signaling in anterior cingulate cortex in chronic pain with depression-like behavior. |
| PubMedID- 20556211 | Moreover, chronic pain commonly coincides with depression and sleep disturbance, as well as mood and anxiety disorders. |
| PubMedID- 21687553 | However, passive coping strategies have been reported to co-vary with psychological distress and depression in patients with chronic pain (nicassio, radojevic, schoenfeldd-smith, & dwyer, 1995). |
| PubMedID- 23688830 | The present study evaluated the efficacy of a clinician-guided internet-delivered cognitive behaviour therapy (icbt) program, the pain course, to reduce disability, anxiety, and depression associated with chronic pain. |
| PubMedID- 22759645 | The madrs has previously been used to make the diagnosis of depression in patients with chronic pain conditions [10]. |
| PubMedID- 21565408 | Assessing depression in patients with chronic pain: a comparison of three rating scales. |
| PubMedID- 22412082 | This study aimed to examine the possible cross-sectional mediating role of sleep in the relationship of gratitude with depression and anxiety in patients with chronic pain. |
| PubMedID- 21808861 | These results suggest that several forms of depression comorbid with chronic pain may be associated with normal st levels. |
| PubMedID- 22198556 | Intracerebroventricular 4-methylcatechol (4-mc) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (bdnf). |
| PubMedID- 24313728 | Pilot feasibility study of a brief, tailored mobile health intervention for depression among patients with chronic pain. |
| PubMedID- 24993763 | Secondary outcomes will include: pain intensity, depression, global impression of change, acceptance of chronic pain and quality of life. |
| PubMedID- 20370845 | Persistent chronic pain is associated with depression and anxiety, interference with work and personal relationships and loss of independence (2). |
| PubMedID- 22546240 | Patients with depression are often diagnosed with chronic pain conditions and vice versa [79]. |
| PubMedID- 22612913 | Anxiety and depression are often associated with chronic pain [20]. |
| PubMedID- 25380222 | Individualized guided internet-delivered cognitive-behavior therapy for chronic pain patients with comorbid depression and anxiety: a randomized controlled trial. |
| PubMedID- 26397881 | Background: assessment of depression in chronic pain patients by self-rating questionnaires developed and validated for use in normal and/or psychiatric populations is common. |
| PubMedID- 20361062 | Aim: to investigate post-traumatic stress, pain intensity, depression, and anxiety in patients with injury-related chronic pain before and after participating in multimodal pain rehabilitation. |
| PubMedID- 21349447 | depression coexisted with chronic pain, and patients reported serious impairment in physical, occupational, and social function an average of 5 years after the onset of chronic pain. |
| PubMedID- 24555569 | Non-steroidal anti-inflammatory drugs and opioids are analgesics used for acute pain, and also anticonvulsants and antidepressants are used as supplementary analgesics for convulsions and depression associated with chronic pain [1-4]. |
| PubMedID- 24992348 | Background: chronic pain is associated with increased anxiety, depression, and maladaptive behaviors, especially in adolescents. |
| PubMedID- 25301891 | The study also revealed greater prevalence of anxiety and depression in patients with chronic pain (p < .05). |
| PubMedID- 22629287 | Finally, chronic pain may be associated with major depression, which complicates treatment, and which must be diagnosed and independently treated for successful pain management. |
| PubMedID- 20603250 | Aims: the aim of this study was to determine if chronic pain patients with symptoms of depression could be identified by one single question. |
| PubMedID- 21957830 | Undertreated depression in chronic pain patients receiving opioid medications may explain suboptimal improvement in pain and functional status despite increasing opioid dosage. |
| PubMedID- 25865734 | Background: chronic pain (cp) patients with depression typically exhibit worse post-treatment outcomes than nondepressed cp patients. |
| PubMedID- 21110860 | A further research study by ohayon et al found that a painful physical condition persisting for longer than 6 months could contribute to the prolongation of a depressive episode, and recommended evaluation of depression for patients with chronic pain [33]. |
| PubMedID- 20587002 | Supporting this conclusion are the clinical data indicating that drugs acting as both antidepressants and analgesics (for example, tricyclics or serotonin-norepinephrine reuptake inhibitors) are equally effective analgesics in chronic pain conditions in patients with and without depression [8]. |
| PubMedID- 21241528 | Conclusion: our data suggests that, among elderly persons, there is a differential association of depression with chronic pain that is related to the anatomical site of the pain. |
| PubMedID- 23805183 | Results: common symptoms (such as pain intensity, depression, and anxiety) in patients with chronic pain showed great variability across subjects and 60% of the cohort had normal values with respect to depressive and anxiety symptoms. |
| PubMedID- 21337796 | [the effectiveness of therapeutic touch on pain, depression and sleep in patients with chronic pain: clinical trial]. |
| PubMedID- 21668746 | Interestingly, chronic pain is often associated with depression and anxiety, and they seem to reinforce each other [29,30]. |
| PubMedID- 23273826 | Cognitive behavioral therapy, self-efficacy, and depression in persons with chronic pain. |
| PubMedID- 24341916 | The literature indicates that chronic pain patients with untreated depression respond poorly to pain treatment [31,32]. |
| PubMedID- 25810926 | In patients treated for depression, the prevalence of chronic pain is reported to be 51.8–59.1% [6–8]. |
| PubMedID- 20140940 | In this study, we examined the overlap between pain and depression in a sample of 342 chronic pain patients treated at a specialty pain clinic. |
| PubMedID- 22448948 | Anxiety and depression often coexist with chronic pain. |
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