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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease chronic myeloproliferative disease
Comorbidity C0740394|hyperuricemia
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PubMedID- 20370912 Exclusion criteria included: secondary hyperuricemia (for example, due to myeloproliferative disorder); xanthinuria; severe renal impairment (eclcr <30 ml/minutes [37,38]); alanine aminotransferase and aspartate aminotransferase values >1.5 times the upper limit of normal; consumption of more than 14 alcoholic drinks per week or a history of alcoholism or drug abuse within five years; or a medical condition that, in the investigator's opinion, would interfere with treatment, safety, or adherence to the protocol.

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