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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease chronic myeloproliferative disease
Comorbidity C0001815|bone marrow fibrosis
Sentences 3
PubMedID- 20200965 (16) pdgf-a has been shown to play a role in the etiology of fibrosis during tissue regeneration and a wide variety of pathologic conditions, including bone marrow fibrosis in patients with myeloproliferative diseases.
PubMedID- 25757677 The jak1 and jak2 inhibitor ruxolitinib has approved indications in myelofibrosis, a bcr-ab1-negative myeloproliferative neoplasm associated with progressive bone marrow fibrosis and shortened survival.
PubMedID- 21296418 bone marrow fibrosis in myeloproliferative neoplasms-associated myelofibrosis: deconstructing a myth.

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