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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease chronic myelocytic leukemia
Comorbidity C0023418|leukemia
Sentences 13
PubMedID- 26043219 They are mainly found in acute myeloid leukemia and blastic phase of philadelphia chromosome-positive chronic myeloid leukemia, more rarely in myelodysplastic syndromes.
PubMedID- 22184394 Hairy cell leukemia variant in a patient with chronic myeloid leukemia receiving nilotinib: sequential or coincidental.
PubMedID- 24152491 Occurrence of chronic lymphocytic leukemia in patients with chronic myelogenous leukemia.
PubMedID- 21302443 Objective: to study the proliferative inhibition effects of imatinib, daunorubicin and bortezomib on two leukemia cell lines with ph(+), chronic myelogenous leukemia cell line k562 expressing p210 protein and acute lymphoblastic leukemia cell line sup-b15 expressing p190 protein.
PubMedID- 20377918 Introduction: the development of philadelphia chromosome (ph) negative acute leukemia/myelodysplastic syndrome (mds) in patients with ph-positive chronic myeloid leukemia (cml) is very rare.
PubMedID- 23192016 Using a collection of 55 leukemia patients treated with tki therapy (chronic myeloid leukemia, n=47; acute lymphoblastic leukemia, n=8), we found that dasatinib, a second-generation broad-spectrum tki, induced a rapid, dose-dependent and substantial mobilization of non-leukemic lymphocytes and monocytes in blood peaking 1-2 h after an oral intake and the blood counts closely mirrored drug plasma concentration.
PubMedID- 21393960 Exfoliative dermatitis with leukemia cutis in a patient with chronic myeloid leukemia: a rare association.
PubMedID- 26256879 [development of ph negative acute myeloid leukemia in a patient with minor-bcr/abl positive chronic myeloid leukemia achieving a partial cytogenetic response during tyrosine kinase inhibitor treatment].
PubMedID- 20922786 Tyrosine kinase inhibitor (tki) treatment targeting breakpoint cluster region-abelson murine leukemia virus, the cause of chronic myeloid leukemia (cml), has revolutionized therapy for patients with this disease.
PubMedID- 24891015 However, patients with bcr-abl1(+) acute lymphoblastic leukemia and subsets of patients with chronic myeloid leukemia are at high risk of relapse despite kinase inhibition therapy, necessitating novel treatment strategies.
PubMedID- 25745544 Bone involvement can also rarely occur in acute lymphoblastic leukemia and blast crisis of chronic myeloid leukemia.12 other tumor presenting with predominant bone destruction at this age is ewing’s sarcoma.
PubMedID- 23738923 Objective: molecular monitoring using quantitative polymerase chain reaction (qpcr) of bcr-abl mrna transcripts using the international scale (is) is recommended by the national comprehensive cancer network and the european leukemianet for patients with chronic myelogenous leukemia in chronic phase (cml-cp).
PubMedID- 22543830 Philadelphia-negative acute promyelocytic leukemia in a patient with chronic myeloid leukemia in complete cytogenetic response after treatment with tyrosine kinase inhibitor.

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