eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cardiomyopathy |
| Comorbidity | C0011847|diabetes |
| Sentences | 32 |
| PubMedID- 22187379 | diabetes is often associated with a specific cardiomyopathy characterized by alterations in systolic and diastolic function as well as microangiopathy. |
| PubMedID- 24083804 | Development of a cardiomyopathy in diabetes mellitus is independent of traditional risk factors, with no clinical trials targeting specific therapeutic interventions. |
| PubMedID- 20813091 | A fetal dilated and hypertrophic cardiomyopathy associated with maternal gestational diabetes--a case report. |
| PubMedID- 21094196 | This may provide a clue for therapy for myocardial disease in diabetes mellitus. |
| PubMedID- 20811489 | The diastolic dysfunction is most likely the result of the higher preponderance of pre-existing hypertension/raised blood pressure and diabetes in patient with ms. hypertensive cardiomyopathy in its various stages has a predominant impact on diastolic rather than systolic function. |
| PubMedID- 24690487 | Among these, alström syndrome (alms; omim #203800) is an autosomal recessive multi-systemic disorder characterized by cone rod-dystrophy resulting in blindness in early childhood, progressive hearing impairment, infantile or adolescent onset dilated cardiomyopathy, metabolic defects leading to hyperinsulinemia, hypertriglyceridaemia, type-2-diabetes mellitus, and obesity[3], and progressive pulmonary, hepatic and renal dysfunction[4]. |
| PubMedID- 20414371 | To date, the mcp-1 –2518 a>g polymorphism has been associated with coronary artery disease, nonfamilial idiopathic dilated cardiomyopathy, carotid atherosclerosis in patients with type 2 diabetes, myocardial infarction, ischemic heart disease, and hypertension [33–38]. |
| PubMedID- 26185602 | Independent of hypertension and coronary artery disease, diabetes is associated with a specific cardiomyopathy, known as diabetic cardiomyopathy (dcm). |
| PubMedID- 21525446 | cardiomyopathy in diabetes is characterized by the presence of myocardial dysfunction in the absence of cad and hypertension (16). |
| PubMedID- 22300387 | Recent evidence suggests that cardiac diseases such as hypertension, coronary artery disease, congestive heart failure, and diabetic cardiomyopathy are associated with diabetes and hyperglycemia. |
| PubMedID- 25889404 | The predominant feature in cardiomyopathy associated with diabetes, metabolic syndrome and ir seems to be the left ventricular diastolic dysfunction as shown in the present study and indicated in previous works [18,19]. |
| PubMedID- 21897899 | This study was taken upto find outthe prevalence of diabetic cardiomyopathy in patients with diabetes mellitus in manipur and its correlation with different parameters like obesity, blood pressure, lipids, duration of diabetes, and glycemic control. |
| PubMedID- 24614171 | Many studies have shown that mitochondrial biogenesis and function are impaired in lipotoxic cardiomyopathy associated with obesity and diabetes [23], and that mitochondrial dysfunction is linked to cardiac dysfunction [24]. |
| PubMedID- 21159162 | Background: apoptosis is an early event involved in cardiomyopathy associated with diabetes mellitus. |
| PubMedID- 23961319 | There is a growing body of evidence that diabetes mellitus leads to a specific cardiomyopathy apart from vascular disease and bring about high morbidity and mortality throughout the world. |
| PubMedID- 23543004 | Hiv infection, diabetes mellitus, history of ischemic cardiomyopathy, and undergoing percutaneous coronary intervention were associated in univariate analysis with occurrence of heart failure. |
| PubMedID- 22166644 | Effects of valsartan on diabetic cardiomyopathy in rats with type 2 diabetes mellitus. |
| PubMedID- 23930867 | Objective: to determine the frequency of diabetic cardiomyopathy among patients with type-2 diabetes presenting with overt heart failure. |
| PubMedID- 20809935 | Currently, several clinical trials using pfd for various diseases have been completed; these include studies on pulmonary fibrosis associated with hermansk-pudlak syndrome, focal segmental glomerulosclerosis, idiopathic pulmonary fibrosis, hypertrophic cardiomyopathy, kidney disease in patients with diabetes, neurofibromatosis type 1, plexiform neurofibromas, and fibrosis caused by radiation therapy for cancer. |
| PubMedID- 24621572 | Assuming that the development of cardiomyopathy in patients with diabetes may take years and furthermore be accelerated by the co-existence of arterial hypertension and coronary artery disease [26], our study population might be too young to detect cardiac abnormalities. |
| PubMedID- 23473489 | diabetes is independently associated with a specific cardiomyopathy, characterized by impaired cardiac muscle relaxation and force development. |
| PubMedID- 21403831 | Several models are available to study atherosclerosis and cardiomyopathy associated with diabetes, including apoe−/− and ldlr −/− mice in which type 1 diabetes is induced by streptozotocin or viral injection [33, 34]. |
| PubMedID- 20467928 | This review focuses on the mechanistic approach to understand the molecular basis of diabetic cardiomyopathy in patients with type 2 diabetes mellitus. |
| PubMedID- 21470409 | In fact, clinical studies have demonstrated that diabetes, with consequent cardiomyopathy and cardiovascular neuropathy, is an independent risk factor for cardiovascular disease and is associated with a 2- to 4-fold increased risk of coronary heart disease [2]. |
| PubMedID- 24389129 | Ang 1-7 represents a promising therapy for diabetic cardiomyopathy associated with type 2 diabetes mellitus. |
| PubMedID- 21492425 | In addition, type 2 diabetes mellitus is associated with a cardiomyopathy characterised by left ventricular hypertrophy (lvh) and diastolic dysfunction [3]. |
| PubMedID- 25936316 | Immunoadsorption can improve cardiac function in transplant candidates with non-ischemic dilated cardiomyopathy associated with diabetes mellitus. |
| PubMedID- 22621761 | While diabetes leads to cardiomyopathy in later stages with hypocontractility and reduced serca activity [6], we have observed increased contractility in earlier stages of type 2 diabetes mellitus [7]. |
| PubMedID- 24416343 | Accordingly, we hypothesized that type 2 diabetes will lead to cardiomyopathy only in the presence of co-morbid factors such as hypertension. |
| PubMedID- 23196711 | Obesity-related diabetes mellitus leads to lipotoxic cardiomyopathy resulting in a form of cardiac dysfunction. |
| PubMedID- 21842146 | Multiple studies have suggested that diabetes is associated with a cardiomyopathy characterized by diastolic abnormalities [26, 27••] and higher chamber stiffness, independent of hypertension and cad [25, 28•]. |
| PubMedID- 25671766 | Thus, carbamylation and uremic cardiomyopathy are associated in patients with diabetes mellitus and kidney disease. |
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