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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cadasil
Comorbidity C0020538|hypertension
Sentences 3
PubMedID- 24344756 Recently found that the cadasil patients with hypertension had a significantly higher prevalence of cerebral infarction and ich and significantly greater numbers of cmbs than without hypertension [18].
PubMedID- 26543744 Recently found that cadasil patients with hypertension had a significantly higher prevalence of stroke, and experienced significantly greater numbers of cmbs than those without hypertension (choi et al.
PubMedID- 20386637 The initial detection may be even more difficult in asian populations for several reasons:26,33,46 1) asians show a lower prevalence of migraine, 2) studies from asian regions describe a lower involvement (22-43%) of the anterior temporal lobe in brain mri, and 3) the high prevalence of vascular risk factors for svd such as hypertension in patients with cadasil increases the difficulty of differentially diagnosing cadasil in asian patients.

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