eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | c syndrome |
| Comorbidity | C0028754|obesity |
| Sentences | 307 |
| PubMedID- 20532017 | In female cases, the incidence of metabolic syndrome associated with obesity after menopause increases rapidly, primarily because of the accumulation of abdominal body fat due to the sudden reduction in estrogen secretion caused by menopause [27]. |
| PubMedID- 21187874 | Evaluated the association of metabolic syndrome with obesity measures, metabolic profiles, and intake of dietary fatty acids. |
| PubMedID- 23556000 | Normal weight obesity is associated with metabolic syndrome and insulin resistance in young adults from a middle-income country. |
| PubMedID- 20526390 | The high prevalence of metabolic syndrome may be attributed to abdominal obesity and dyslipidemia characterized by high triglycerides and low hdl cholesterol (table 3). |
| PubMedID- 22333076 | [epidemiological study on the association between obesity with metabolic syndrome in obese children and adolescents of nanning city, guangxi]. |
| PubMedID- 20302640 | In addition, cerebellar degeneration can be caused by systemic diseases such as diabetes mellitus [74], chronic alcoholism [75], or obesity with metabolic syndrome [45,46]. |
| PubMedID- 22303323 | These have revealed a relationship between maternal obesity and the onset of the metabolic syndrome in the offspring. |
| PubMedID- 24598991 | The results for women were consistent with previous studies that found that lower openness to experience is likely to be associated with obesity and the presence of metabolic syndrome [6], [10], [37]. |
| PubMedID- 24060348 | Studies that investigated weight management in adults were obesity is attributed to specific genetic syndromes such as prader-willi syndrome, cohen syndrome or bardet-biedl syndrome were also excluded. |
| PubMedID- 22694047 | The prevalence of the metabolic syndrome with attendant morbid obesity continues to increase nationwide. |
| PubMedID- 23805900 | Associations of cardiorespiratory fitness, physical activity, and obesity with metabolic syndrome in hong kong chinese midlife women. |
| PubMedID- 23648313 | obesity is closely associated with the metabolic syndrome (mets) and subsequent low-grade inflammation links to endothelial dysfunction (ed) and cardiovascular disease. |
| PubMedID- 21593202 | obesity is the hallmark of the metabolic syndrome and represents a major global health problem that frequently associates with the development of chronic diseases, including type 2 diabetes and cardiovascular disease (1). |
| PubMedID- 24321125 | obesity is strongly associated with metabolic syndrome, which is characterized by the presence of insulin resistance, hypertension, and hyperlipidemia. |
| PubMedID- 20061420 | obesity without established comorbidities of the metabolic syndrome is associated with a proinflammatory and prothrombotic state, even before the onset of puberty in children. |
| PubMedID- 25888859 | Nash is considered the hepatic manifestation of the metabolic syndrome and is associated with central obesity, insulin resistance, diabetes, essential hypertension, and dyslipidemia [17,18].we have previously shown that serum levels of ages are elevated under oxidative stress, inflammatory, and/or diabetic conditions and correlated with insulin resistance and decreased adiponectin levels, thereby being one of the useful biomarkers for differentiating nash from simple steatosis [19-24]. |
| PubMedID- 20576133 | Childhood obesity heightens childhood risk of metabolic syndrome, indicating that prevention of early onset obesity may substantially reduce the prevalence of metabolic syndrome in youth and their future risk of life-threatening conditions such as diabetes and cardiovascular disease [4]. |
| PubMedID- 23734506 | [age dependence of metabolic syndrome association with obesity types among women]. |
| PubMedID- 25995613 | The rest of the components of metabolic syndrome, including obesity, elevated triglycerides, low hdl, and fasting glucose, were seen in equal prevalence among diabetics with and without diabetic retinopathy and among diabetics with npdr and pdr (figure 1, tables 2 and 3). |
| PubMedID- 23383064 | Metabolic syndrome is associated with visceral obesity, insulin resistance and an increased risk of cardiovascular diseases. |
| PubMedID- 23819808 | Background: it has been well documented that obesity is closely associated with metabolic syndrome (mets). |
| PubMedID- 23206662 | In humans, evidence suggests that the obesity-related morbidities associated with metabolic syndrome, including diabetes and cardiovascular disease, are caused by an increase in the production of advanced glycoxidation end-products (ages). |
| PubMedID- 25922847 | Thus, the ability of adipose tissue to expand and match the storage needs of energy surplus may be a key determinant in protection against the metabolic syndrome associated with obesity [72]. |
| PubMedID- 22277141 | While obesity is associated with the metabolic syndrome, some obese individuals do not possess the constellation of the metabolic abnormalities and are referred to as metabolically healthy but obese (mho) persons. |
| PubMedID- 24567686 | As metabolic syndrome correlates directly with obesity andsedentary lifestyles, health education for patients is of significant importance in theself-management of risk factors, such as obesity, high blood pressure, and smoking10). |
| PubMedID- 21525818 | Most patients with nafld have risk factors such as insulin resistance, obesity or other indications of metabolic syndrome. |
| PubMedID- 26000287 | However, eat weight in the fg group was higher than that in the st group; this result was consistent with abdominal obesity typically associated with metabolic syndrome. |
| PubMedID- 20514046 | Alstrom syndrome is a rare genetic syndrome associated with early-onset obesity, severe insulin resistance (ir) that is disproportionate to the degree of adiposity and premature diabetes. |
| PubMedID- 24217719 | Objective: to test the hypothesis that overweight and obesity with and without metabolic syndrome are associated with increased risk of mi and ihd. |
| PubMedID- 25648511 | Fibre is the largest component of the seaweed biomass [10,11] and therefore may be present in sufficient amounts when included in the diet to prevent metabolic syndrome associated with obesity, type 2 diabetes and cardiovascular complications [12]. |
| PubMedID- 20852030 | We hypothesized that overweight and obesity, regardless of metabolic syndrome status, as well as the metabolic syndrome, regardless of bmi status, would be associated with long-term increased risk for diabetes. |
| PubMedID- 26064924 | Young rats that received the cafeteria diet for 8 weeks developed metabolic syndrome along with obesity, higher hepatic weight, increased plasma levels of glucose, insulin and triglycerides, and insulin resistance [57]. |
| PubMedID- 20516702 | These results indicate the urgent need to reduce abdominal obesity, an important indicator of the metabolic syndrome, in kuwaiti adolescents. |
| PubMedID- 24334510 | One important finding is that childhood obesity is highly associated with adult metabolic syndrome, type 2 diabetes, and cardiovascular diseases. |
| PubMedID- 22150400 | This association was mainly driven by the central obesity component of the metabolic syndrome. |
| PubMedID- 21765599 | (23,24) if xylitol stimulates lipogenesis, it might induce steatosis and obesity, leading to metabolic syndrome. |
| PubMedID- 24809933 | Accumulating evidence indicates that visceral fat obesity is located upstream of the metabolic syndrome and atherosclerosis910. |
| PubMedID- 21540583 | Background: hyperlipidemia and obesity are associated with metabolic syndrome and increased risk in developing diabetes and cardiovascular disease. |
| PubMedID- 25191539 | obesity, which can lead to the metabolic syndrome, has recently gained attention as a factorthat dramatically increases the risk of arteriosclerotic disease. |
| PubMedID- 25714610 | With more than 1.4 billion overweight or obese adults worldwide, obesity and progression of the metabolic syndrome are major health and economic challenges. |
| PubMedID- 24265520 | Another current hypothesis proposes that obesity is associated with metabolic syndrome, which activates molecular processes that are mitogenic in breast epithelial cells and stimulates neoplasia. |
| PubMedID- 21921649 | To elucidate adult bodily responses in bfmi860 mice that develop juvenile obesity, we studied features of the metabolic syndrome at 20 weeks. |
| PubMedID- 20156345 | Sedentary behaviour, such as time spent sitting is positively associated with coronary heart disease risk factors, obesity, and development of the metabolic syndrome [3,4]. |
| PubMedID- 22144985 | This in utero programming seems to create a kind of “metabolic memory,” since physiological anomalies of gestational period are responsible for the onset of diseases in offspring at adulthood, such as type 2 diabetes and obesity associated with metabolic syndrome. |
| PubMedID- 21396586 | This review describes the genetic syndromes associated with obesity and overgrowth. |
| PubMedID- 22125617 | It is strongly associated to components of the metabolic syndrome including obesity, insulin resistance, dyslipidemia and type 2 diabetes mellitus (t2dm) [2], and it is estimated that up to one third of the general population in western societies may have hepatic steatosis [3]. |
| PubMedID- 26554109 | The aim of this study was to determine the relationships between serum adiponectin levels and parameters of both insulin sensitivity and obesity in patients with the metabolic syndrome and/or coronary artery disease, as well as to assess predictive value of adiponectin serum levels as a biomarker of these entitetis. |
| PubMedID- 25760026 | Insulin resistance is a common pathological state found in the metabolic syndromeassociated with obesity and type 2 diabetes mellitus, in which target tissues fail torespond properly to physiologic insulin levels (5,7). |
| PubMedID- 24064364 | Epidemiological data indicate that an adverse maternal environment during pregnancy predisposes offspring to metabolic syndrome with increased obesity, and type 2 diabetes. |
| PubMedID- 22967456 | In addition, it has been reported that prenatally undernourished rats nursed by control mothers exhibit a rapid catch-up growth and are more susceptible to developing obesity and features of metabolic syndrome [58]. |