eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | c syndrome |
| Comorbidity | C0004153|atherosclerosis |
| Sentences | 42 |
| PubMedID- 20705925 | Methods and results: atm(+/-)/apoe(-/-) mice developed accelerated atherosclerosis and multiple features of the metabolic syndrome, including hypertension, hypercholesterolemia, obesity, steatohepatitis, and glucose intolerance. |
| PubMedID- 20727144 | Subclinical carotid atherosclerosis is associated with metabolic syndrome [38]. |
| PubMedID- 24072083 | Carotid intima-media thickness (imt) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (ms). |
| PubMedID- 20039893 | The metabolic syndrome is associated with subclinical atherosclerosis independent of insulin resistance: the guangzhou biobank cohort study-cvd. |
| PubMedID- 21772967 | Another wasid substudy [76] has demonstrated that metabolic syndrome is associated with intracranial atherosclerosis and confers a higher risk of major vascular events in these patients. |
| PubMedID- 19762024 | Objective: metabolic syndrome (ms) is associated with subclinical atherosclerosis, but the relative role of obstructive sleep apnoea (osa) is largely unknown. |
| PubMedID- 22813569 | Association of metabolic syndrome with carotid atherosclerosis in the young north indian population. |
| PubMedID- 24470352 | Also observed defects in akt2 signaling which may contribute to accelerated atherosclerosis in patients with metabolic syndrome (18). |
| PubMedID- 23798936 | A recent population-based study reported that the association of a metabolic syndrome with subclinical atherosclerosis was independent of its association with the biomarkers of endothelial damage and oxidative stress. |
| PubMedID- 25242580 | Therefore, the intervention with anti-inflammatory agents may effectively delay the formation and progression of atherosclerosis in patients with metabolic syndrome. |
| PubMedID- 23746122 | In addition, these results indicate that increased mpo activity is associated with an oxidant-antioxidant imbalance that may contribute to atherosclerosis in patients with adult nephrotic syndrome. |
| PubMedID- 24089156 | Objectives: we studied the carotid parameters as early indicators of atherosclerosis in children with nephrotic syndrome. |
| PubMedID- 25633268 | Aims: matrix metalloproteinases (mmps) and their tissue inhibitors (timps) are dysregulated in metabolic syndrome (mets) and associated with atherosclerosis and cardiovascular disease (cvd). |
| PubMedID- 22493605 | Background: the renin-angiotensin-aldosterone system plays an important role in the development and progression of hypertension and accelerated atherosclerosis (atheroscleropathy) associated with the cardiorenal metabolic syndrome and type 2 diabetes mellitus. |
| PubMedID- 24065256 | Objectives: we measured the carotid intima-media thickness, a surrogate marker of early atherosclerosis, in patients with carpal tunnel syndrome compared to a control group to evaluate the risk of atherosclerotic disease. |
| PubMedID- 20187939 | Low hdl is often accompanied by insulin resistance, obesity, and hypertension, which are risk factors for atherosclerosis and are components of the metabolic syndrome [23,43]. |
| PubMedID- 20398632 | Background: oxidative stress induced by free fatty acids plays a critical role in the pathogenesis of endothelial dysfunction and atherosclerosis in patients with metabolic syndrome. |
| PubMedID- 25233795 | Association of metabolic syndrome with coronary atherosclerosis in non-diabetic postmenopausal women. |
| PubMedID- 21497934 | Aim: the goal of this study was to investigate the association between omentin-1 and carotid atherosclerosis in patients with metabolic syndrome (mets). |
| PubMedID- 21669554 | Apolipoprotein e−/− (apoe−/−) mice heterozygous in atm developed accelerated atherosclerosis and multiple features of the metabolic syndrome including glucose intolerance, hypertension, obesity and hypercholesterolemia [22,23]. |
| PubMedID- 21321616 | [detection of the parameters for early atherosclerosis in patients with metabolic syndrome and periodontitis]. |
| PubMedID- 25546822 | Interestingly, therefore, myd88-dependent cooperation between myeloid and endothelial cells was recently proven to be key to the promotion of the vascular inflammation and atherosclerosis associated with metabolic syndrome 64. thus, because myd88 is likely to be a key player in integrating cross-talk among tlr, fcr, and complement receptors, in concert with the reduction in igg and c3a deposition, our finding that es-62 and anti–il-22 down-regulate myd88 expression in kidney cells provides an effective mechanism for protecting against kidney inflammation. |
| PubMedID- 25951321 | Klotho did not show any beneficial effects on atherosclerosis and components of the metabolic syndrome and was associated with increased plasma cholesterol levels. |
| PubMedID- 24481091 | [relation between mean platelet volume and subclinical atherosclerosis in patients with metabolic syndrome]. |
| PubMedID- 21827549 | Background: carotid intima-media thickness (cimt) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (mets). |
| PubMedID- 23398954 | We aimed to study the association of chemokine cxcl16/cxcr6 and carotid atherosclerosis in patients with metabolic syndrome. |
| PubMedID- 22291799 | In our study, the level of inflammatory markers crp and tnf-α, agents of the coagulation system activation and fibrinolysis (d-dimers, fibrinogen) participating in the inflammatory process of atherosclerosis were higher in patients with the metabolic syndrome as compared with healthy women. |
| PubMedID- 21505504 | Our results suggest that these processes are associated with atherosclerosis independent of metabolic syndrome. |
| PubMedID- 20689417 | Recent findings: individuals infected with hiv frequently demonstrate a metabolic syndrome associated with atherosclerosis and cardiovascular disease. |
| PubMedID- 23776788 | [2] il-6 has also been reported to play a role in the development of atherosclerosis complications in patients with metabolic syndrome. |
| PubMedID- 19968738 | This combination of metabolic syndrome factors was associated with accelerated atherosclerosis due to increased accumulation of macrophages in association with endothelial dysfunction demonstrated by increased expression of vcam-1 and icam-1 in the aorta of dko mice [49]. |
| PubMedID- 20470376 | Association between serum levels of incretins, glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip), and metabolic syndrome components in patients with atherosclerosis-prone conditions. |
| PubMedID- 23514998 | Acute thrombosis after atherosclerotic plaque disruption is a major complication of primary atherosclerosis, leading to acute ischemic syndromes and atherosclerotic progression. |
| PubMedID- 25218813 | Circulating osteoprotegerin is increased in the metabolic syndrome and associates with subclinical atherosclerosis and coronary arterial calcification. |
| PubMedID- 23409033 | Implication of progranulin and c1q/tnf-related protein-3 (ctrp3) on inflammation and atherosclerosis in subjects with or without metabolic syndrome. |
| PubMedID- 22748277 | Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in asian indians. |
| PubMedID- 22765047 | Ir and other features of the metabolic syndrome independently associate with atherosclerosis in ra [46]. |
| PubMedID- PMC4089697 | Conclusion: these results indicate that increased myeloperoxidase activity is associated with an oxidant-antioxidant imbalance that may contribute to atherosclerosis in patients with adult nephrotic syndrome. |
| PubMedID- 21816063 | Furthermore, our findings suggest that the observed association between uric acid and carotid atherosclerosis may be attributed to metabolic syndrome-dependent and -independent mechanisms. |
| PubMedID- 24490696 | Tempol attenuates atherosclerosis associated with metabolic syndrome via decreased vascular inflammation and nadph-2 oxidase expression. |
| PubMedID- 23245314 | Decreased serum obestatin consequent upon trib3 q84r polymorphism exacerbates carotid atherosclerosis in subjects with metabolic syndrome. |
| PubMedID- 21251304 | Circulating interleukin-18: a specific biomarker for atherosclerosis-prone patients with metabolic syndrome. |
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