eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | c syndrome |
| Comorbidity | C0003950|ascariasis |
| Sentences | 1 |
| PubMedID- 21869914 | We infer that intestinal parasites may trigger voc by direct affectation of the lungs and impairment of oxygenation during the pulmonary migratory phase as seen in loffler’s syndrome commonly associated with ascariasis and ancylostomiasis.68,69 loffler’s syndrome typically presents with parasitic and eosinophilic pulmonary infiltrates, consolidations and reactive bronchospasm.68,69 these pathological processes that are associated with loffler’s syndrome can eventually lead to a fall in pao2, generalized hypoxia, increased red cell sickling, decreased pulmonary conversion of deoxy-hbs to oxy-hbs, failure of reversal of sickled red cells to discocytes, piling of sickled cells and voc. |
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