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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease bronchopulmonary dysplasia
Comorbidity C0023529|periventricular leukomalacia
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PubMedID- 26483217 The composite outcome (mortality during nicu stay or any severe neonatal morbidity such as intraventricular hemorrhage grades 3-4, periventricular leukomalacia, retinopathy of prematurity stages 3-5, bronchopulmonary dysplasia and necrotizing enterocolitis stages 2-3) decreased significantly for sites with decreased (or=0.89, 95% ci=0.85-0.93) or null (or=0.94, 95% ci=0.90-0.98) ni trends, but no significant trends in the composite outcome were detected for sites with increased ni rates.
PubMedID- 25825965 Multivariable logistic regression analyses compared a composite outcome indicating a mortality or major morbidity (severe intraventricular hemorrhage, periventricular leukomalacia, severe retinopathy of prematurity, bronchopulmonary dysplasia, or necrotizing enterocolitis) between networks, according to pda diagnosis and treatment, and tested the association between pda treatment and the composite outcome within networks.

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