eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | beta-thalassemia |
| Comorbidity | C0282193|iron overload |
| Sentences | 15 |
| PubMedID- 25671931 | Comparison of deferiprone and deferrioxamine for the treatment of transfusional iron overload in children with beta thalassemia major. |
| PubMedID- 25922644 | We recommend that regardless of the amount of iron overload in patients with beta thalassemia major that have shown some degree of fibrosis in their liver biopsy before transplantation, appropriate steps should be taken to reduce iron overload as soon as possible after successful transplantation. |
| PubMedID- 25601433 | Genetic modifiers of secondary iron overload in beta thalassemia major. |
| PubMedID- 24790662 | iron overload in beta thalassaemia major and intermedia patients. |
| PubMedID- 21791471 | This study evaluates whether iron overload in patients with beta thalassemia intermedia is associated with morbidity. |
| PubMedID- 25161967 | Background: diabetes mellitus is a major complication of iron overload in patients with beta thalassemia major. |
| PubMedID- 20383704 | These results imply that combining the atrial ejection force index with the transmitral-derived echocardiographic assessment is a feasible way to detect early stages of myocardial iron overload in patients with beta thalassemia major. |
| PubMedID- 22645668 | A study done on status of thyroid function and iron overload in patients with beta thalassemia major on deferoxamine in jordan concluded that there is significantly high (p < 0.05) levels of serum ferritin, ft3, zinc, and copper in patients with beta thalassemia major as compared to controls [13]. |
| PubMedID- 23056717 | Objective: dilated cardiomyopathy is the end result of chronic iron overload in patients with beta thalassemia major. |
| PubMedID- 25402221 | The effects of deferasirox on renal haemodynamics, including glomerular filtration rate (gfr) and renal plasma flow (rpf), were investigated in a phase i, open-label study in beta thalassaemia major patients with iron overload. |
| PubMedID- 24575259 | Background: frequent blood transfusion in patients with beta thalassemia major can lead to iron overload especially in liver. |
| PubMedID- 26205801 | Objectives: 'the aim of this work was to compare the efficacy of different iron chelating agents' in the treatment of ' iron overload in children with beta thalassemia major'. |
| PubMedID- 19460052 | Aims: to assess the significance of cardiac iron overload in patients with beta thalassaemia. |
| PubMedID- 19838709 | This is the first study to prove the role of gst gene deletions with iron overload in hbe/beta thalassemia. |
| PubMedID- 25293426 | Early heart iron overload in beta thalassemia major patients can be quantified through t2* cardiovascular magnetic resonance (cmr). |
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