eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | autosomal dominant polycystic kidney disease |
| Comorbidity | C0022661|chronic kidney disease |
| Sentences | 4 |
| PubMedID- 22425799 | chronic kidney disease progression in patients with autosomal dominant polycystic kidney disease. |
| PubMedID- 24007508 | adpkd is the cause of chronic kidney disease (ckd) in 5% of patients undergoing renal replacement therapy (rrt) in the usa [4], a rate that rises to 7.9% in our geographic area [5]. |
| PubMedID- 19887788 | Methods: 101 adpkd patients with chronic kidney disease stages 1-5 were recruited and gfr was measured with the (51)cr-edta clearance method, and estimated with the modification of diet in renal disease study (mdrd) equation with 4 variables, the chronic kidney disease epidemiology collaboration (ckd-epi) equation, the cockcroft-gault equation adjusted for body surface area and the mdrd equation with cystatin c. |
| PubMedID- 26407729 | Tolvaptan is the first pharmaceutical agent to be approved in europe for delaying the progression of adpkd in adults with stage 1-3 chronic kidney disease at initiation of treatment. |
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