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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease atypical mole
Comorbidity C0025202|melanoma
Sentences 12
PubMedID- 24130172 In fact, kai1 expression is drastically reduced in primary melanoma compared with dysplastic nevi (p = 1.8x10(-4)) and further reduced in metastatic melanoma compared with primary melanoma (p = 9.4 x 10(-15)).
PubMedID- 24927342 Wang et al11 showed decreased ing3 expression in malignant melanoma in comparison with dysplastic nevi and gunduz et al1228 found allelic loss and reduced expression of the ing3 in human head and neck cancers, in line with our findings.
PubMedID- 22970236 Also revealed that nuclear p27kip1 expression was reduced in primary melanomas compared with dysplastic nevi and further reduced in metastatic melanoma, whereas the cytoplasmic p27kip1 was increased in primary and metastatic melanomas compared with dysplastic nevi [18].
PubMedID- 23381582 Our data showed that fbw7 expression is significantly reduced in primary melanoma compared with dysplastic nevi (p=0.020) and further reduced in metastatic melanoma compared with primary melanoma (p=0.011).
PubMedID- 25954957 The results showed that nrp1 expression was significantly reduced in common nevi and dysplastic nevi, compared with primary melanoma and metastatic melanoma.
PubMedID- 24075545 Early diagnosis of melanoma in atypical mole syndrome patients, however, may be challenging.
PubMedID- 21647268 In addition, sox4 expression was reduced in metastatic malignant melanoma compared with dysplastic nevi and primary melanoma.
PubMedID- 24499631 Showed that nqo1 expression is significantly increased in primary melanomas compared with dysplastic nevi and this may occur in the initiation stage of melanoma development[23].
PubMedID- 20952589 Sox4 expression was remarkably reduced in metastatic melanoma compared with dysplastic nevi (p < 0.05) and primary melanoma (p < 0.01).
PubMedID- 22287410 This is only the second case reported to date of primary malignant melanoma in dysplastic nevus syndrome.
PubMedID- 25752663 Background: digital follow-up is a useful method for the detection of melanoma in atypical mole syndrome patients.
PubMedID- 25389923 Little is known about melanoma-related worry in patients with atypical mole syndrome (ams).

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