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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease ataxia
Comorbidity C0009806|constipation
Sentences 3
PubMedID- 20656061 The sensitivity and specificity of dre for identifying dyssynergia in patients with chronic constipation were 75% and 87%, respectively; the positive predictive value was 97%.
PubMedID- 22807692 Another point to emphasize is that linaclotide is unlikely to benefit in patients with pelvic floor dyssynergia, another cause of chronic constipation that responds poorly to laxatives.
PubMedID- 23018003 Finally, data on the clinical management of patients with constipation due to pelvic floor dyssynergia and on the safety and efficacy of prucalopride in patients with severe constipation were also of interest.

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