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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease aortic valve insufficiency
Comorbidity C0020538|hypertension
Sentences 6
PubMedID- PMC4044781 While systemic hypertension and pre-operative diagnosis of aortic insufficiency were correlated with worsened lv circumferential strain, this study could not detect a relationship between aortic stiffness and global measures of lv systolic function.
PubMedID- 24839447 aortic regurgitation with systemic hypertension, male sex, thinned or fragile aortic wall, and ascending aortic dilatation were reported as a risk factor previously [3, 4].
PubMedID- 24753835 Rarely however, when unusually large or multiple, they can lead to massive aortic regurgitation (ar), mostly in patients with chronic hypertension and/or aortic annular dilation.
PubMedID- 26184749 Attenuated early diastolic interventricular septum bulging by pulmonary hypertension due to later developed aortic regurgitation.
PubMedID- 24397918 [6] reported that aortic regurgitation combined with systemic hypertension, male sex, and a thinned or fragile aorta with mild dilatation (>45 mm) at initial avr may be risk factors for late aortic complications.
PubMedID- 21170625 Conclusion: aortic regurgitation combined with systemic hypertension, male sex, and thinned or fragile aortic walls in patients with ascending aortic dilatation (>/=45 mm diameter) at the time of avr may be predisposing factors for postsurgical aortic complications.

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