eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | anaplastic large cell lymphoma |
| Comorbidity | C0026986|myelodysplastic syndromes |
| Sentences | 1 |
| PubMedID- 20877721 | Npm1 fusion proteins are also specifically involved: t(5;17)(q35;q21)/npm1-rara causes acute promyelocytic leukemia; t(2;5)(p23;q35)/npm1-alk underlies anaplastic large cell lymphoma; t(3;5)(q26;q35)/npm1-mlf1 is associated with myelodysplastic syndromes (mds) and aml with trilineage dysplasia and poor prognosis (http://atlasgeneticsoncology.org). |
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