eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | anal fistula |
| Comorbidity | C0010346|crohn\'s disease |
| Sentences | 36 |
| PubMedID- 24471303 | Anti-tnf drugs are proven to be effective and indicated only for treatment of perianal fistulas in patients with crohn's disease. |
| PubMedID- 25425534 | Aim: combined infliximab and sphincter-sparing surgery can be effective in perianal fistula associated with crohn's disease (cd). |
| PubMedID- 20186945 | Background: adenocarcinoma arising from perianal fistulae in patients with crohn's disease (cd) is rare. |
| PubMedID- 22956209 | Sexual function and quality of life after surgical treatment for anal fistulas in crohn's disease. |
| PubMedID- 22816055 | Surgical and medical treatments have some roles in the treatment of perianal fistulas in patients with crohn's disease. |
| PubMedID- 24707131 | The use of rectal endoscopic ultrasound has been expanded for imaging of perianal fistulae in patients with crohn's disease and appears much more sensitive than magnetic resonance imaging and exam under anesthesia. |
| PubMedID- 25213810 | Azathioprine induced epstein barr virus-positive mucocutaneous ulcer arising in perianal fistula and abscess associated with crohn's disease. |
| PubMedID- 25663759 | Management of perianal fistulas in crohn's disease: an up-to-date review. |
| PubMedID- 20178792 | Fibrin glue is effective healing perianal fistulas in patients with crohn's disease. |
| PubMedID- 23053677 | Purpose: the management of perianal fistula in patients with crohn's disease is an extremely challenging medical problem as many fistulas do not respond to available treatments. |
| PubMedID- 22507755 | Conclusion: this study provides a new 3d endoanal ultrasound criterion, cufs, of perianal fistula in patients with crohn's disease. |
| PubMedID- 24026400 | Health care costs of complex perianal fistula in crohn's disease. |
| PubMedID- 24447625 | Background and aims: treatment of complex perianal fistulas associated with crohn's disease is challenging. |
| PubMedID- 26147989 | The nod2 single nucleotide polymorphism rs72796353 (ivs4+10 a>c) is a predictor for perianal fistulas in patients with crohn's disease in the absence of other nod2 mutations. |
| PubMedID- 25309057 | Treatment of peri-anal fistula in crohn's disease. |
| PubMedID- 19834976 | Perianal fistulae in crohn's disease: current and future approaches to treatment. |
| PubMedID- 22513437 | Future trials with improved study design (including prospective data collection and consideration of verification bias) may help to further clarify the role of mri in the assessment and treatment response monitoring of perianal fistulas (particularly in patients with crohn's disease). |
| PubMedID- 25115149 | Conclusions: combined surgical and medical (anti-tnf-alpha +/- immunomodulators) therapy may have additional beneficial effects on perianal fistula healing in patients with crohn's disease, compared with surgery or medical therapy alone. |
| PubMedID- 21899707 | Aim: perianal fistulae in crohn's disease are frequently complex, involve the anal sphincter complex and surgical treatment can be associated with poor healing of wounds and damage to the mechanism of continence. |
| PubMedID- 26264168 | Perianal fistulas in crohn's disease are common and difficult to treat. |
| PubMedID- 23207597 | Stem cell therapy for perianal fistulas in patients with crohn's disease is a promising new therapy approach. |
| PubMedID- 20466103 | Background: anal fistulas in patients with crohn's disease are especially difficult to manage because of nonhealing and incontinence. |
| PubMedID- 25485513 | Background: data regarding the effectiveness of adalimumab (ada) in the treatment of perianal fistula in patients with crohn's disease (cd) naive to antitumor necrosis factor (tnf) therapy are scarce. |
| PubMedID- 23459533 | [management of rectal cancer including cancer in the anal fistula with crohn's disease]. |
| PubMedID- 26116801 | Allogeneic bone marrow-derived mesenchymal stromal cells promote healing of refractory perianal fistulas in patients with crohn's disease. |
| PubMedID- 25975971 | Background: healing rates after surgical closure for high perianal fistula in patients with crohn's disease are even more disappointing than in patients with cryptoglandular fistulas. |
| PubMedID- 24187625 | A later phase ii trial in perianal fistulae both with crohn's disease origin or cryptoglandular origin was conducted in 49 patients using mscs from lipoaspirates, with an effectiveness of 71% and a recurrence of 17.6% after one-year follow-up regardless of the origin of the fistula [60]. |
| PubMedID- 21761164 | Background: the aim of the study was a cross-sectional investigation into the types of anal fistulae in patients with crohn's disease using 3-dimensional endoanal ultrasonography. |
| PubMedID- 26289163 | Multimodal treatment of perianal fistulas in crohn's disease: seton versus anti-tnf versus advancement plasty (pisa): study protocol for a randomized controlled trial. |
| PubMedID- 22405167 | Background and aim: appropriate treatment of perianal fistulas in crohn's disease (cd) involves accurate anatomic evaluation. |
| PubMedID- 22992478 | [surgical treatment of anal fistulas in crohn's disease]. |
| PubMedID- 21640988 | [mucinous adenocarcinoma over an anorectal fistula in a patient with crohn's diseases]. |
| PubMedID- 26557938 | Current management of anal fistulas in crohn's disease. |
| PubMedID- 22640732 | Is it always crohn's disease in a patient with perianal fistulae and skip lesions in the colon. |
| PubMedID- 20351996 | Three patients had a primary or recurrent perianal fistula with associated crohn's disease [figure 2]. |
| PubMedID- 26311275 | Cumulative evidence that mesenchymal stem cells promote healing of perianal fistulas of patients with crohn's disease-going from bench to bedside. |
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