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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease american trypanosomiasis
Comorbidity C0018801|heart failure
Sentences 22
PubMedID- 20802940 Introduction: to evaluate physical capacity as determined by the six-minute walk test (6mwt) in patients with chronic heart failure due to chagas' disease associated with systemic arterial hypertension (chagas-sah).
PubMedID- 22811738 In situ expression of regulatory cytokines by heart inflammatory cells in chagas' disease patients with heart failure.
PubMedID- 23871619 Cardiopulmonary exercise and 6-min walk tests as predictors of quality of life and long-term mortality among patients with heart failure due to chagas disease.
PubMedID- 22011801 Conclusion: the prevalence of asymptomatic coronary artery disease in patients with severe heart failure due to chagas disease is low and among the risk factors for coronary heart disease, smoking was the most prevalent.
PubMedID- 22513344 heart failure survival score in patients with chagas disease: correlation with functional variables.
PubMedID- 24627740 chagas disease, a major cause of heart failure (hf) in latin america, affects approximately eight million people[1] and represents a significant public health and socio-economic problem in these countries.
PubMedID- 20385875 chagas' disease, the leading cause of heart failure in latin america, is caused by the kinetoplastid protozoan trypanosoma cruzi.
PubMedID- 21820551 Treatment options for heart failure due to chagas disease are not different from standard therapy.
PubMedID- 23152267 Authors' conclusions: this cochrane review has found a lack of evidence on the effects of carvedilol for treating heart failure in patients with chagas disease.
PubMedID- 21484040 chagas disease was the cause of heart failure in 92 (20.4%) patients who had higher b type natriuretic peptide levels (1,978.38 vs. 1,697.64 pg/ml; p = 0.015).
PubMedID- 22558095 Luis fabrega” in santiago city in may of 2010. the patient came from el pantano community, one of our evaluated areas, and presented a heart failure compatible with chronic chagas disease and a positive serology for t. cruzi.
PubMedID- 20502520 Nearly 60% of symptomatic congestive heart failure was due to chagas disease; mortality was also higher for infected than uninfected patients.
PubMedID- 26407508 After a decade or more, 20% to 30% of people will experience chronic cardiovascular chagas disease with sequelae including heart failure, arrhythmias, and thromboembolism.
PubMedID- 25886035 If untreated, chagas disease can lead to heart failure and death.
PubMedID- 24984860 Introduction: new therapeutic options are necessary for patients with chronic chagas disease, a leading cause of heart failure in latin american countries.
PubMedID- 23787193 Methods: we retrospectively analyzed the outcome of 54 chagas disease patients without heart failure and with left ventricular (lv) ejection fraction >45% whose tgf-beta1 serum values were determined between january 1998 and december 1999.
PubMedID- 23272265 In human clinical studies of patients with end-stage heart failure due to chagas disease the administration of autologous bone marrow mononuclear cells did not improve cardiac function [19].
PubMedID- 24918914 Our data suggest that patients with heart failure due to chagas disease and class iiiand iv heart failure submitted to transplantation of stem cells from bone marrow to themyocardium, showed no increase in the incidence of sustained ventricular tachycardia,but showed increase in nonsustained ventricular tachycardia between holter atrandomization and holter at 6 months in the study group, as well as increased vpbdensity in the study group.
PubMedID- 20006935 Accordingly, in this study we compare outcomes in chagas' disease with non-chagas'-disease-related advanced heart failure among patients on the waiting list for heart transplantation.
PubMedID- 21359478 Background: heart failure due to chagas' disease (hfcd) is a progressive inflammatory cardiomyopathy that affects millions of individuals in latin america.
PubMedID- 23031286 Conclusion: altogether our results demonstrate that heart failure in chagas' disease may occur due to electrical and mechanical remodeling of cardiac myocytes, and suggest that akt/pi3k/no axis could be an important pharmacological target to improve the disease outcome.
PubMedID- 20591516 Conclusion: b-blockers are effective, not detrimental, and may improve survival in chagas' disease patients with chronic heart failure.

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