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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease adrenal adenoma
Comorbidity C0001622|hypercortisolism
Sentences 5
PubMedID- 26161451 Context: long-term follow-up studies revealed that patients with subclinical hypercortisolism (sh) due to adrenocortical adenomas have an increased incidence of cardiovascular diseases and mortality.
PubMedID- 22267278 Aim: to evaluate the prevalence of hypertension, type 2 diabetes (t2d), coronary heart disease (chd), ischemic stroke, osteoporosis, and fractures, and their relationship to increasing patterns of subclinical hypercortisolism, in patients with nonsecreting adrenal adenomas (nsa) and scs.
PubMedID- 23620612 Cushing's syndrome is an uncommon but potentially reversible cause of dilated cardiomyopathy, most often reported in patients with hypercortisolism arising from an adrenal adenoma1–2.
PubMedID- 26035405 Prediction of adrenal adenomas with hypercortisolism by using adrenal computed tomography: emphasis on contralateral adrenal thinning.
PubMedID- 26139209 Despite somatic prkaca mutations being a common finding in patients with clinically manifest cushing's syndrome, the pathogenesis of adrenocortical adenomas associated with subclinical hypercortisolism seems to rely on a different molecular background.

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