eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | adenomatous polyposis coli |
| Comorbidity | C0001418|adenocarcinomas |
| Sentences | 2 |
| PubMedID- 26097892 | The transition of normal epithelial mucosa to polyps (any grossly visible protrusion from the mucosal surface of the colon) or adenomas (also known as adenomatous polyps) to adenocarcinomas is well-established in patients with familial adenomatous polyposis (fap) (tsao et al., 2004). |
| PubMedID- 24885408 | In the current study, relationships between tumor angiogenesis and multi-step carcinogenesis were assessed using the apcmin/+ mouse model, which spontaneously develops multiple intestinal adenomas that mimic those that undergo early transformation into adenocarcinomas in patients with familial adenomatous polyposis[25]. |
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