eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | adenocarcinoma of esophagus |
| Comorbidity | C0028754|obesity |
| Sentences | 5 |
| PubMedID- 20632267 | Background: obesity is associated with oesophageal adenocarcinoma, but mechanisms linking fat and carcinogenesis remain poorly understood. |
| PubMedID- 22969802 | Prior studies have indicated the positive link between dietary fat as well as obesity and the risk of oesophageal adenocarcinoma [43–45], but little evidence has been reported regarding the role of serum lipids. |
| PubMedID- 22306944 | Serum igf-1 linking visceral obesity with esophageal adenocarcinoma: unconvincing evidence. |
| PubMedID- 22121096 | Mmp9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation. |
| PubMedID- 22972011 | Background: esophageal adenocarcinoma is often associated with obesity, and a 5 kg m(-2) increase in body mass index (bmi) has, in fact, been found to be strongly associated with the risk of this type of cancer (rr, 1.52; p < 0.0001). |
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