eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | adenocarcinoma of esophagus |
| Comorbidity | C0004763|barrett esophagus |
| Sentences | 3 |
| PubMedID- 21593708 | Incidence of esophageal adenocarcinoma with barrett esophagus (be) imposes a decision about therapy management. |
| PubMedID- 24570883 | Advanced esophageal adenocarcinomas arising from barrett esophagus (be) are tumors with an increasing incidence and poor prognosis. |
| PubMedID- 25621687 | The incidence of esophageal adenocarcinoma arising from barrett esophagus (be) has been rapidly increasing in many western countries over the past few decades.1–3 it also leads to increasing the rate of hospitalization for esophageal adenocarcinoma and causes a serious problem.4 endoscopic surveillance of be, the currently accepted standard, aims to reduce morbidity and mortality by early detection and endoscopic therapy of dysplasia or cancer.5–8 current guidelines from gastroenterology societies recommend endoscopic surveillance of be using white light endoscopy (wle) with targeted biopsies of any endoscopically visible lesions and 4 random quadrant biopsies from every 2 cm of the be segment (seattle protocol).7,9 however, it has been pointed out that this protocol has several limitations, such as time required, low compliance, and increased risk of sampling error.10 therefore, establishment of a more effective surveillance program for detecting dysplastic lesions or those with high malignant potential in be patients is highly desirable. |
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