eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | acute promyelocytic leukemia |
| Comorbidity | C0035078|renal failure |
| Sentences | 3 |
| PubMedID- 21656902 | Arsenic trioxide for the treatment of a relapsed acute promyelocytic leukemia with acute renal failure. |
| PubMedID- 23078653 | Conclusion: arsenic trioxide can be used safely and effectively to treat acute promyelocytic leukemia in patients with advanced renal failure using careful monitoring of side effects rather than blood levels of arsenic to guide therapeutic dosing. |
| PubMedID- 25600167 | Objective: to determine the potential for arsenic trioxide (ato) to be safely and effectively incorporated into induction therapy of newly diagnosed acute promyelocytic leukaemia (apl) in patients with severe chronic renal failure (crf) by reduction of the ato dosage to compensate for reduced renal elimination of arsenic in crf. |
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