eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | acute megakaryoblastic leukemia |
| Comorbidity | C0027022|myeloproliferative disorder |
| Sentences | 3 |
| PubMedID- 22296450 | Transient myeloproliferative disorder (tmd) of the newborn and acute megakaryoblastic leukaemia (amkl) in children with down syndrome (ds) represent paradigmatic models of leukaemogenesis. |
| PubMedID- 20697343 | Transient myeloproliferative disorder (tmd) leading to acute megakaryoblastic leukaemia (amkl) account for more than half of all myeloid leukaemias in ds, with an × 500 increased incidence relative to euploid children (zipursky et al., 1994; al-kasim et al., 2002; taub and ravindranath, 2002). |
| PubMedID- 23045682 | Trisomy 21 is associated with hematopoietic abnormalities in the fetal liver, a preleukemic condition termed transient myeloproliferative disorder, and increased incidence of acute megakaryoblastic leukemia. |
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