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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease acromegaly
Comorbidity C0206754|neuroendocrine tumors
Sentences 2
PubMedID- 24119925 In less than 2% of the cases, acromegaly results from ghrh-secreting neuroendocrine tumors usually located in the lungs, thymus and endocrine pancreas [1,2].
PubMedID- 25834454 To avoid this issue, octreotide long-acting release (lar) and lanreotide autogel are now available, both of which can be administered monthly in cases of acromegaly or patients with neuroendocrine tumors.35,49 this is available also for pasireotide, and the lar formulation is expected to produce fewer peak-to-trough fluctuations than the subcutaneous formulation, which could reduce the drug’s adverse effects, such as nausea and hyperglycemia.

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