eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | acromegaly |
| Comorbidity | C0020619|hypogonadism |
| Sentences | 2 |
| PubMedID- 25873948 | hypogonadism occurs frequently in patients with acromegaly as a consequence of prl and gh hypersecretion or hypopituitarism due to local mass effects [25]. |
| PubMedID- 24550687 | These hypersecretory activities are associated with hypogonadism, infertility, acromegaly, cushing's disease and hyperthyroidism 17,18. previous studies of pituitary tumors have identified several mutations that, by activating oncogenes or inactivating tumor suppressors, could be involved in tumorigenesis 30. however, a general mechanism for the origin of pituitary tumors remains obscure. |
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