eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | achalasia |
| Comorbidity | C0007137|squamous cell carcinoma |
| Sentences | 2 |
| PubMedID- 25674530 | The overall prevalence of esophageal squamous cell carcinoma in patients with achalasia has been estimated to be 3%, accounting for a 50-fold increase in cancer risk.7 in a recent, large prospective cohort study with long-term (mean, 15 years) follow-up data of 448 achalasia patients, the relative hazard ratio for the development of esophageal cancer in achalasia was 28.8 although many cases of esophageal carcinoma in patients with diverticula have been reported, the precise level of cancer risk in esophageal diverticulum remains to be elucidated. |
| PubMedID- 25664812 | On the basis of prior data, the overall prevalence of esophageal squamous cell carcinoma in patients with achalasia has been estimated to be up to 8.6%, accounting for a 50-fold increase in cancer risk [9]. |
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